SNP Detail Info-rs3917449

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0298 (8907/29882,GnomAD)
A=0306 (8930/29118,TOPMED)
A=0383 (1918/5008,1000G)
A=0242 (933/3854,ALSPAC)
A=0229 (848/3708,TWINSUK)

Position: chr1:169722078 (GRCh38.p7) (1q24.2)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 3 Enhancers around

Promoter: 7 Promoters around

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.629	A=0.371
1000Genomes	American	Sub	694	G=0.620	A=0.380
1000Genomes	East Asian	Sub	1008	G=0.498	A=0.502
1000Genomes	Europe	Sub	1006	G=0.717	A=0.283
1000Genomes	Global	Study-wide	5008	G=0.617	A=0.383
1000Genomes	South Asian	Sub	978	G=0.620	A=0.380
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.758	A=0.242
The Genome Aggregation Database	African	Sub	8680	G=0.656	A=0.344
The Genome Aggregation Database	American	Sub	838	G=0.570	A=0.430
The Genome Aggregation Database	East Asian	Sub	1606	G=0.548	A=0.452
The Genome Aggregation Database	Europe	Sub	18458	G=0.742	A=0.257
The Genome Aggregation Database	Global	Study-wide	29882	G=0.701	A=0.298
The Genome Aggregation Database	Other	Sub	300	G=0.690	A=0.310
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.693	A=0.306
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.771	A=0.229

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs3917449	0.0000535	alcoholism	pha002891
rs3917449	0.0000535	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
Chr1:169691219	RN7SL333P	ENSG00000239494.2	G>A	3.6310e-3	-137678	Cerebellar_Hemisphere

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr1	169663053	169664067	E071	-27152
chr1	169664116	169664389	E071	-26830
chr1	169661474	169662757	E074	-28462

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr1	169680599	169681493	E067	-9726
chr1	169680599	169681493	E068	-9726
chr1	169680599	169681493	E069	-9726
chr1	169680599	169681493	E071	-9726
chr1	169680599	169681493	E072	-9726
chr1	169680599	169681493	E073	-9726
chr1	169680599	169681493	E074	-9726

rs3917449