rs393459

Homo sapiens
T>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0101 (3052/29954,GnomAD)
G=0139 (4065/29118,TOPMED)
G=0139 (697/5008,1000G)
G=0008 (31/3854,ALSPAC)
G=0005 (19/3708,TWINSUK)
chr7:134285692 (GRCh38.p7) (7q33)
AD
GWASdb2
1   publication(s)
See rs on genome
143 Enhancers around
14 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.134285692T>G
GRCh37.p13 chr 7NC_000007.13:g.133970444T>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.666G=0.334
1000GenomesAmericanSub694T=0.950G=0.050
1000GenomesEast AsianSub1008T=0.851G=0.149
1000GenomesEuropeSub1006T=0.991G=0.009
1000GenomesGlobalStudy-wide5008T=0.861G=0.139
1000GenomesSouth AsianSub978T=0.940G=0.060
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.992G=0.008
The Genome Aggregation DatabaseAfricanSub8702T=0.702G=0.298
The Genome Aggregation DatabaseAmericanSub838T=0.920G=0.080
The Genome Aggregation DatabaseEast AsianSub1612T=0.853G=0.147
The Genome Aggregation DatabaseEuropeSub18500T=0.991G=0.008
The Genome Aggregation DatabaseGlobalStudy-wide29954T=0.898G=0.101
The Genome Aggregation DatabaseOtherSub302T=0.970G=0.030
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.860G=0.139
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.995G=0.005
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs3934590.000961alcohol dependence21314694

eQTL of rs393459 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs393459 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr7133973287133973404E0672843
chr7133973620133973675E0673176
chr7133973753133973879E0673309
chr7133974944133975006E0674500
chr7133975183133975302E0674739
chr7133979017133979090E0678573
chr7133979517133979589E0679073
chr7133979765133979805E0679321
chr7133983504133983574E06713060
chr7133983712133984150E06713268
chr7133984161133984234E06713717
chr7133984286133984372E06713842
chr7133984900133984954E06714456
chr7133985689133985746E06715245
chr7133985829133985944E06715385
chr7133986050133986344E06715606
chr7133986360133986583E06715916
chr7133986943133987216E06716499
chr7133973287133973404E0682843
chr7133973620133973675E0683176
chr7133973753133973879E0683309
chr7133979017133979090E0688573
chr7133979517133979589E0689073
chr7133983504133983574E06813060
chr7133983712133984150E06813268
chr7133984161133984234E06813717
chr7133984286133984372E06813842
chr7133985689133985746E06815245
chr7133985829133985944E06815385
chr7133986050133986344E06815606
chr7133986360133986583E06815916
chr7133974944133975006E0694500
chr7133975183133975302E0694739
chr7133979017133979090E0698573
chr7133979517133979589E0699073
chr7133979765133979805E0699321
chr7133983504133983574E06913060
chr7133983712133984150E06913268
chr7133984161133984234E06913717
chr7133984286133984372E06913842
chr7133984900133984954E06914456
chr7133985689133985746E06915245
chr7133985829133985944E06915385
chr7133986050133986344E06915606
chr7133986360133986583E06915916
chr7133986943133987216E06916499
chr7133968038133968088E070-2356
chr7133968267133968338E070-2106
chr7133969667133969759E070-685
chr7133982853133982903E07012409
chr7133983504133983574E07013060
chr7133983712133984150E07013268
chr7133984900133984954E07014456
chr7133973620133973675E0713176
chr7133973753133973879E0713309
chr7133979017133979090E0718573
chr7133979517133979589E0719073
chr7133979765133979805E0719321
chr7133983504133983574E07113060
chr7133983712133984150E07113268
chr7133984161133984234E07113717
chr7133984286133984372E07113842
chr7133985829133985944E07115385
chr7133986050133986344E07115606
chr7133986360133986583E07115916
chr7133986943133987216E07116499
chr7133973620133973675E0723176
chr7133973753133973879E0723309
chr7133974944133975006E0724500
chr7133975183133975302E0724739
chr7133979017133979090E0728573
chr7133979517133979589E0729073
chr7133979765133979805E0729321
chr7133983504133983574E07213060
chr7133983712133984150E07213268
chr7133984161133984234E07213717
chr7133984286133984372E07213842
chr7133984900133984954E07214456
chr7133986050133986344E07215606
chr7133986360133986583E07215916
chr7133999890133999997E07229446
chr7133932794133932986E073-37458
chr7133933023133933283E073-37161
chr7133973753133973879E0733309
chr7133979017133979090E0738573
chr7133983504133983574E07313060
chr7133983712133984150E07313268
chr7133984161133984234E07313717
chr7133986050133986344E07315606
chr7133986360133986583E07315916
chr7133973287133973404E0742843
chr7133973620133973675E0743176
chr7133973753133973879E0743309
chr7133979017133979090E0748573
chr7133979517133979589E0749073
chr7133979765133979805E0749321
chr7133982853133982903E07412409
chr7133983504133983574E07413060
chr7133983712133984150E07413268
chr7133984161133984234E07413717
chr7133984286133984372E07413842
chr7133984900133984954E07414456
chr7133985075133985308E07414631
chr7133985689133985746E07415245
chr7133985829133985944E07415385
chr7133986050133986344E07415606
chr7133986360133986583E07415916
chr7133986943133987216E07416499
chr7134012691134012963E07442247
chr7133932794133932986E081-37458
chr7133933023133933283E081-37161
chr7133939154133939322E081-31122
chr7133939351133939608E081-30836
chr7133939645133940330E081-30114
chr7133940623133940883E081-29561
chr7133941300133941354E081-29090
chr7133941365133941425E081-29019
chr7133968267133968338E081-2106
chr7133969667133969759E081-685
chr7133983504133983574E08113060
chr7133983712133984150E08113268
chr7133984161133984234E08113717
chr7133984286133984372E08113842
chr7133984900133984954E08114456
chr7133985075133985308E08114631
chr7133986050133986344E08115606
chr7133986360133986583E08115916
chr7133931203133931303E082-39141
chr7133931307133931448E082-38996
chr7133932335133932375E082-38069
chr7133932794133932986E082-37458
chr7133933023133933283E082-37161
chr7133939351133939608E082-30836
chr7133969667133969759E082-685
chr7133970251133970301E082-143
chr7133970575133970625E082131
chr7133970764133970840E082320
chr7133983504133983574E08213060
chr7133983712133984150E08213268
chr7133984161133984234E08213717
chr7133984286133984372E08213842
chr7133985689133985746E08215245
chr7133986050133986344E08215606










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr7133974145133974509E0673701
chr7134000513134002630E06730069
chr7134000513134002630E06830069
chr7133974145133974509E0693701
chr7134000513134002630E06930069
chr7134000513134002630E07030069
chr7133974145133974509E0713701
chr7134000513134002630E07130069
chr7133974145133974509E0723701
chr7134000513134002630E07230069
chr7134000513134002630E07330069
chr7134000513134002630E07430069
chr7134000513134002630E08130069
chr7134000513134002630E08230069