rs3957336

Homo sapiens
G>C
None
Check p-value
SNV (Single Nucleotide Variation)
G==0435 (8774/20147,GnomAD)
G==0345 (1304/3775,1000G)
C=0457 (1694/3708,TWINSUK)
C=0469 (1354/2889,ALSPAC)
chrX:3963903 (GRCh38.p7) (Xp22.33)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
2 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr XNC_000023.11:g.3963903G>C
GRCh37.p13 chr XNC_000023.10:g.3881944G>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1003G=0.366C=0.634
1000GenomesAmericanSub524G=0.230C=0.770
1000GenomesEast AsianSub764G=0.100C=0.900
1000GenomesEuropeSub766G=0.490C=0.510
1000GenomesGlobalStudy-wide3775G=0.345C=0.655
1000GenomesSouth AsianSub718G=0.500C=0.500
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide2889G=0.531C=0.469
The Genome Aggregation DatabaseAfricanSub5571G=0.366C=0.634
The Genome Aggregation DatabaseAmericanSub612G=0.190C=0.810
The Genome Aggregation DatabaseEast AsianSub984G=0.100C=0.900
The Genome Aggregation DatabaseEuropeSub12801G=0.502C=0.497
The Genome Aggregation DatabaseGlobalStudy-wide20147G=0.435C=0.564
The Genome Aggregation DatabaseOtherSub179G=0.480C=0.520
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.543C=0.457
PMID Title Author Journal

P-Value

SNP ID p-value Traits Study
rs39573360.0000168alcohol consumptionpha001401
rs39573360.0000295alcohol consumptionpha001399
rs39573360.0000408alcohol consumptionpha001397

eQTL of rs3957336 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
ChrX:3881944RP11-706O15.3ENSG00000234449.2G>C2.8728e-481586Frontal_Cortex_BA9
ChrX:3881944RP11-706O15.3ENSG00000234449.2G>C8.7672e-481586Hypothalamus
ChrX:3881944RP11-706O15.3ENSG00000234449.2G>C4.9788e-481586Hippocampus
ChrX:3881944RP11-706O15.3ENSG00000234449.2G>C6.1587e-581586Nucleus_accumbens_basal_ganglia

meQTL of rs3957336 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chrX38804623881333E068-611
chrX38804623881333E071-611