rs395843

Homo sapiens
T>C
LOC105378102 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T==0177 (5302/29946,GnomAD)
T==0152 (4453/29118,TOPMED)
T==0157 (784/5008,1000G)
T==0248 (957/3854,ALSPAC)
T==0261 (967/3708,TWINSUK)
chr6:164057884 (GRCh38.p7) (6q26)
AD
GWASdb2
1   publication(s)
See rs on genome
162 Enhancers around
1 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.164057884T>C
GRCh37.p13 chr 6NC_000006.11:g.164478916T>C

Gene: LOC105378102, uncharacterized LOC105378102(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC105378102 transcriptXR_943213.2:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.040C=0.960
1000GenomesAmericanSub694T=0.140C=0.860
1000GenomesEast AsianSub1008T=0.230C=0.770
1000GenomesEuropeSub1006T=0.235C=0.765
1000GenomesGlobalStudy-wide5008T=0.157C=0.843
1000GenomesSouth AsianSub978T=0.170C=0.830
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.248C=0.752
The Genome Aggregation DatabaseAfricanSub8718T=0.080C=0.920
The Genome Aggregation DatabaseAmericanSub838T=0.180C=0.820
The Genome Aggregation DatabaseEast AsianSub1614T=0.198C=0.802
The Genome Aggregation DatabaseEuropeSub18474T=0.220C=0.779
The Genome Aggregation DatabaseGlobalStudy-wide29946T=0.177C=0.822
The Genome Aggregation DatabaseOtherSub302T=0.180C=0.820
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.152C=0.847
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.261C=0.739
PMID Title Author Journal
21529783A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.Heath ACBiol Psychiatry

P-Value

SNP ID p-value Traits Study
rs3958436.9E-05alcoholism (heaviness of drinking)21529783

eQTL of rs395843 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs395843 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr6164431001164431131E067-47785
chr6164505644164505750E06726728
chr6164522966164523091E06744050
chr6164523236164523650E06744320
chr6164523696164523819E06744780
chr6164523870164524126E06744954
chr6164431354164432648E068-46268
chr6164435376164436074E068-42842
chr6164436126164436466E068-42450
chr6164443735164444085E068-34831
chr6164484441164484682E0685525
chr6164499287164499347E06820371
chr6164499440164500182E06820524
chr6164505203164505253E06826287
chr6164505390164505449E06826474
chr6164505460164505540E06826544
chr6164505644164505750E06826728
chr6164507707164507944E06828791
chr6164507980164508093E06829064
chr6164508144164508238E06829228
chr6164508327164508508E06829411
chr6164508548164508598E06829632
chr6164518187164518475E06839271
chr6164518519164519709E06839603
chr6164522966164523091E06844050
chr6164523236164523650E06844320
chr6164523696164523819E06844780
chr6164431354164432648E069-46268
chr6164489989164490054E06911073
chr6164491794164491866E06912878
chr6164491926164492003E06913010
chr6164502381164502501E06923465
chr6164505203164505253E06926287
chr6164505390164505449E06926474
chr6164505460164505540E06926544
chr6164505644164505750E06926728
chr6164518187164518475E06939271
chr6164518519164519709E06939603
chr6164519761164520885E06940845
chr6164521040164521203E06942124
chr6164521251164521511E06942335
chr6164521574164521628E06942658
chr6164523236164523650E06944320
chr6164523696164523819E06944780
chr6164527951164528018E06949035
chr6164442723164443224E070-35692
chr6164443466164443547E070-35369
chr6164443735164444085E070-34831
chr6164444374164444534E070-34382
chr6164448350164448409E070-30507
chr6164448671164448808E070-30108
chr6164491926164492003E07013010
chr6164492045164492100E07013129
chr6164492414164492454E07013498
chr6164492485164492589E07013569
chr6164492834164492884E07013918
chr6164493077164493127E07014161
chr6164505203164505253E07026287
chr6164505390164505449E07026474
chr6164505460164505540E07026544
chr6164505644164505750E07026728
chr6164518519164519709E07039603
chr6164521040164521203E07042124
chr6164521251164521511E07042335
chr6164521574164521628E07042658
chr6164522966164523091E07044050
chr6164523236164523650E07044320
chr6164523696164523819E07044780
chr6164523870164524126E07044954
chr6164524646164524836E07045730
chr6164524887164525184E07045971
chr6164431354164432648E071-46268
chr6164436126164436466E071-42450
chr6164442723164443224E071-35692
chr6164484441164484682E0715525
chr6164505203164505253E07126287
chr6164505390164505449E07126474
chr6164505460164505540E07126544
chr6164505644164505750E07126728
chr6164518519164519709E07139603
chr6164519761164520885E07140845
chr6164521040164521203E07142124
chr6164521251164521511E07142335
chr6164521574164521628E07142658
chr6164521702164521835E07142786
chr6164522966164523091E07144050
chr6164523236164523650E07144320
chr6164523696164523819E07144780
chr6164523870164524126E07144954
chr6164489381164489498E07210465
chr6164489712164489801E07210796
chr6164489989164490054E07211073
chr6164505390164505449E07226474
chr6164505460164505540E07226544
chr6164505644164505750E07226728
chr6164507707164507944E07228791
chr6164507980164508093E07229064
chr6164521040164521203E07242124
chr6164521251164521511E07242335
chr6164521574164521628E07242658
chr6164522966164523091E07244050
chr6164523236164523650E07244320
chr6164523696164523819E07244780
chr6164523870164524126E07244954
chr6164435376164436074E073-42842
chr6164436483164436701E073-42215
chr6164436746164436786E073-42130
chr6164499156164499271E07320240
chr6164499287164499347E07320371
chr6164499440164500182E07320524
chr6164505203164505253E07326287
chr6164505390164505449E07326474
chr6164505763164507628E07326847
chr6164507707164507944E07328791
chr6164507980164508093E07329064
chr6164508144164508238E07329228
chr6164508327164508508E07329411
chr6164522966164523091E07344050
chr6164455989164456067E074-22849
chr6164457059164457109E074-21807
chr6164457138164457561E074-21355
chr6164498995164499129E07420079
chr6164499156164499271E07420240
chr6164499287164499347E07420371
chr6164499440164500182E07420524
chr6164505203164505253E07426287
chr6164505390164505449E07426474
chr6164505460164505540E07426544
chr6164505644164505750E07426728
chr6164507707164507944E07428791
chr6164507980164508093E07429064
chr6164518187164518475E07439271
chr6164518519164519709E07439603
chr6164521251164521511E07442335
chr6164521574164521628E07442658
chr6164521702164521835E07442786
chr6164522966164523091E07444050
chr6164523236164523650E07444320
chr6164523696164523819E07444780
chr6164523870164524126E07444954
chr6164442723164443224E081-35692
chr6164443466164443547E081-35369
chr6164443735164444085E081-34831
chr6164447887164448182E081-30734
chr6164448256164448306E081-30610
chr6164448350164448409E081-30507
chr6164448671164448808E081-30108
chr6164449072164449117E081-29799
chr6164504890164504942E08125974
chr6164505203164505253E08126287
chr6164505390164505449E08126474
chr6164505460164505540E08126544
chr6164505644164505750E08126728
chr6164505763164507628E08126847
chr6164519761164520885E08140845
chr6164521040164521203E08142124
chr6164521251164521511E08142335
chr6164521574164521628E08142658
chr6164523236164523650E08144320
chr6164523696164523819E08144780
chr6164523870164524126E08144954
chr6164523696164523819E08244780










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr6164525720164527409E06846804