rs3967768

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0174 (5235/29930,GnomAD)
A=0139 (4071/29118,TOPMED)
A=0106 (529/5008,1000G)
A=0198 (764/3854,ALSPAC)
A=0203 (753/3708,TWINSUK)
chr4:163268711 (GRCh38.p7) (4q32.2)
ND
GWASdb2
1   publication(s)
See rs on genome
17 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.163268711G>A
GRCh37.p13 chr 4NC_000004.11:g.164189863G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.926A=0.074
1000GenomesAmericanSub694G=0.910A=0.090
1000GenomesEast AsianSub1008G=0.964A=0.036
1000GenomesEuropeSub1006G=0.770A=0.230
1000GenomesGlobalStudy-wide5008G=0.894A=0.106
1000GenomesSouth AsianSub978G=0.900A=0.100
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.802A=0.198
The Genome Aggregation DatabaseAfricanSub8712G=0.908A=0.092
The Genome Aggregation DatabaseAmericanSub838G=0.870A=0.130
The Genome Aggregation DatabaseEast AsianSub1614G=0.971A=0.029
The Genome Aggregation DatabaseEuropeSub18464G=0.771A=0.228
The Genome Aggregation DatabaseGlobalStudy-wide29930G=0.825A=0.174
The Genome Aggregation DatabaseOtherSub302G=0.820A=0.180
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.860A=0.139
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.797A=0.203
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs39677680.000625nicotine dependence17158188

eQTL of rs3967768 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs3967768 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr4164195227164195407E0705364
chr4164195465164195782E0705602
chr4164196117164196424E0706254
chr4164164939164165056E081-24807
chr4164165110164165232E081-24631
chr4164165841164165895E081-23968
chr4164166815164166909E081-22954
chr4164166926164167083E081-22780
chr4164195227164195407E0815364
chr4164195465164195782E0815602
chr4164196117164196424E0816254
chr4164164939164165056E082-24807
chr4164165110164165232E082-24631
chr4164165324164165715E082-24148
chr4164195227164195407E0825364
chr4164195465164195782E0825602
chr4164196117164196424E0826254