rs400333

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0444 (13303/29900,GnomAD)
G=0416 (12132/29118,TOPMED)
A==0480 (2402/5008,1000G)
G=0356 (1372/3854,ALSPAC)
G=0353 (1310/3708,TWINSUK)
chr10:17309795 (GRCh38.p7) (10p12.33)
AD
GWASdb2
1   publication(s)
See rs on genome
14 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.17309795A>G
GRCh37.p13 chr 10NC_000010.10:g.17351794A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.528G=0.472
1000GenomesAmericanSub694A=0.520G=0.480
1000GenomesEast AsianSub1008A=0.128G=0.872
1000GenomesEuropeSub1006A=0.687G=0.313
1000GenomesGlobalStudy-wide5008A=0.480G=0.520
1000GenomesSouth AsianSub978A=0.540G=0.460
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.644G=0.356
The Genome Aggregation DatabaseAfricanSub8688A=0.525G=0.475
The Genome Aggregation DatabaseAmericanSub830A=0.510G=0.490
The Genome Aggregation DatabaseEast AsianSub1608A=0.132G=0.868
The Genome Aggregation DatabaseEuropeSub18472A=0.604G=0.395
The Genome Aggregation DatabaseGlobalStudy-wide29900A=0.555G=0.444
The Genome Aggregation DatabaseOtherSub302A=0.750G=0.250
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.583G=0.416
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.647G=0.353
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs4003330.000482alcohol dependence21314694

eQTL of rs400333 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs400333 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr101732838517328485E081-23309
chr101732862817328840E081-22954
chr101737052617370576E08118732
chr101737065517370723E08118861
chr101737076317370830E08118969
chr101737093217370972E08119138
chr101737150017372085E08119706
chr101738932717389418E08137533
chr101738949517389535E08137701
chr101738964517389725E08137851
chr101732862817328840E082-22954
chr101738932717389418E08237533
chr101738949517389535E08237701
chr101738964517389725E08237851