SNP Detail Info-rs400333

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0444 (13303/29900,GnomAD)
G=0416 (12132/29118,TOPMED)
A==0480 (2402/5008,1000G)
G=0356 (1372/3854,ALSPAC)
G=0353 (1310/3708,TWINSUK)

Position: chr10:17309795 (GRCh38.p7) (10p12.33)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 14 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 10	NC_000010.11:g.17309795A>G
GRCh37.p13 chr 10	NC_000010.10:g.17351794A>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.528	G=0.472
1000Genomes	American	Sub	694	A=0.520	G=0.480
1000Genomes	East Asian	Sub	1008	A=0.128	G=0.872
1000Genomes	Europe	Sub	1006	A=0.687	G=0.313
1000Genomes	Global	Study-wide	5008	A=0.480	G=0.520
1000Genomes	South Asian	Sub	978	A=0.540	G=0.460
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.644	G=0.356
The Genome Aggregation Database	African	Sub	8688	A=0.525	G=0.475
The Genome Aggregation Database	American	Sub	830	A=0.510	G=0.490
The Genome Aggregation Database	East Asian	Sub	1608	A=0.132	G=0.868
The Genome Aggregation Database	Europe	Sub	18472	A=0.604	G=0.395
The Genome Aggregation Database	Global	Study-wide	29900	A=0.555	G=0.444
The Genome Aggregation Database	Other	Sub	302	A=0.750	G=0.250
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.583	G=0.416
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.647	G=0.353

PMID	Title	Author	Journal
21314694	Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.	Kendler KS	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs400333	0.000482	alcohol dependence	21314694

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr10	17328385	17328485	E081	-23309
chr10	17328628	17328840	E081	-22954
chr10	17370526	17370576	E081	18732
chr10	17370655	17370723	E081	18861
chr10	17370763	17370830	E081	18969
chr10	17370932	17370972	E081	19138
chr10	17371500	17372085	E081	19706
chr10	17389327	17389418	E081	37533
chr10	17389495	17389535	E081	37701
chr10	17389645	17389725	E081	37851
chr10	17328628	17328840	E082	-22954
chr10	17389327	17389418	E082	37533
chr10	17389495	17389535	E082	37701
chr10	17389645	17389725	E082	37851

rs400333