SNP Detail Info-rs4074334

Organism: Homo sapiens

Alleles: T>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

T=0232 (6926/29834,GnomAD)
T=0191 (5589/29118,TOPMED)
T=0248 (1242/5008,1000G)
T=0205 (790/3854,ALSPAC)
T=0208 (771/3708,TWINSUK)

Position: chr4:58939738 (GRCh38.p7) (4q13.1)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 4	NC_000004.12:g.58939738T>G
GRCh37.p13 chr 4	NC_000004.11:g.59805404G>T

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.855	T==0.145
1000Genomes	American	Sub	694	G=0.740	T==0.260
1000Genomes	East Asian	Sub	1008	G=0.606	T==0.394
1000Genomes	Europe	Sub	1006	G=0.752	T==0.248
1000Genomes	Global	Study-wide	5008	G=0.752	T==0.248
1000Genomes	South Asian	Sub	978	G=0.770	T==0.230
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.795	T==0.205
The Genome Aggregation Database	African	Sub	8724	G=0.849	T==0.151
The Genome Aggregation Database	American	Sub	834	G=0.770	T==0.230
The Genome Aggregation Database	East Asian	Sub	1562	G=0.570	T==0.430
The Genome Aggregation Database	Europe	Sub	18412	G=0.746	T==0.253
The Genome Aggregation Database	Global	Study-wide	29834	G=0.767	T==0.232
The Genome Aggregation Database	Other	Sub	302	G=0.750	T==0.250
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.808	T==0.191
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.792	T==0.208

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs4074334	0.00076	alcohol dependence	20201924
rs4074334	0.00095	alcohol dependence(Early Onset)	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs4074334