rs4076851

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
G==0374 (11197/29924,GnomAD)
G==0389 (11348/29118,TOPMED)
G==0399 (1998/5008,1000G)
G==0324 (1249/3854,ALSPAC)
G==0327 (1211/3708,TWINSUK)
chr4:123556545 (GRCh38.p7) (4q28.1)
AD
GWASdb2
1   publication(s)
See rs on genome
28 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.123556545G>A
GRCh37.p13 chr 4NC_000004.11:g.124477700G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.473A=0.527
1000GenomesAmericanSub694G=0.380A=0.620
1000GenomesEast AsianSub1008G=0.355A=0.645
1000GenomesEuropeSub1006G=0.351A=0.649
1000GenomesGlobalStudy-wide5008G=0.399A=0.601
1000GenomesSouth AsianSub978G=0.410A=0.590
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.324A=0.676
The Genome Aggregation DatabaseAfricanSub8710G=0.439A=0.561
The Genome Aggregation DatabaseAmericanSub838G=0.440A=0.560
The Genome Aggregation DatabaseEast AsianSub1614G=0.345A=0.655
The Genome Aggregation DatabaseEuropeSub18462G=0.343A=0.656
The Genome Aggregation DatabaseGlobalStudy-wide29924G=0.374A=0.625
The Genome Aggregation DatabaseOtherSub300G=0.370A=0.630
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.389A=0.610
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.327A=0.673
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs40768510.000104alcohol dependence20201924

eQTL of rs4076851 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4076851 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr4124466572124466681E068-11019
chr4124475731124477442E068-258
chr4124477492124477560E068-140
chr4124520639124522165E06842939
chr4124428381124428522E069-49178
chr4124428628124428719E069-48981
chr4124428723124428893E069-48807
chr4124430094124430709E070-46991
chr4124431066124431304E070-46396
chr4124520209124520626E07042509
chr4124520639124522165E07042939
chr4124522194124522987E07044494
chr4124473884124473947E071-3753
chr4124473985124474099E071-3601
chr4124474250124474300E071-3400
chr4124475396124475540E071-2160
chr4124475614124475690E071-2010
chr4124475731124477442E071-258
chr4124477492124477560E071-140
chr4124509039124510739E07131339
chr4124520209124520626E07142509
chr4124520639124522165E07142939
chr4124475731124477442E073-258
chr4124428628124428719E074-48981
chr4124475614124475690E074-2010
chr4124475731124477442E074-258
chr4124520639124522165E07442939
chr4124522194124522987E07444494