rs4129566

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0107 (3222/29966,GnomAD)
C=0112 (3286/29118,TOPMED)
C=0091 (458/5008,1000G)
C=0135 (520/3854,ALSPAC)
C=0144 (535/3708,TWINSUK)
chr4:173626006 (GRCh38.p7) (4q34.1)
CD
GWASdb2 | GWASCatalog
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.173626006T>C
GRCh37.p13 chr 4NC_000004.11:g.174547157T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.900C=0.100
1000GenomesAmericanSub694T=0.920C=0.080
1000GenomesEast AsianSub1008T=0.995C=0.005
1000GenomesEuropeSub1006T=0.861C=0.139
1000GenomesGlobalStudy-wide5008T=0.909C=0.091
1000GenomesSouth AsianSub978T=0.870C=0.130
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.865C=0.135
The Genome Aggregation DatabaseAfricanSub8728T=0.905C=0.095
The Genome Aggregation DatabaseAmericanSub838T=0.920C=0.080
The Genome Aggregation DatabaseEast AsianSub1620T=0.993C=0.007
The Genome Aggregation DatabaseEuropeSub18478T=0.876C=0.123
The Genome Aggregation DatabaseGlobalStudy-wide29966T=0.892C=0.107
The Genome Aggregation DatabaseOtherSub302T=0.890C=0.110
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.887C=0.112
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.856C=0.144
PMID Title Author Journal
23958962Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene.Gelernter JMol Psychiatry

P-Value

SNP ID p-value Traits Study
rs41295663E-06cocaine dependence23958962

eQTL of rs4129566 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4129566 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.