rs4132806

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
C==0445 (13277/29794,GnomAD)
C==0429 (12515/29118,TOPMED)
C==0438 (2195/5008,1000G)
T=0443 (1708/3854,ALSPAC)
T=0473 (1754/3708,TWINSUK)
chr3:103916591 (GRCh38.p7) (3q13.11)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.103916591C>T
GRCh37.p13 chr 3NC_000003.11:g.103635435C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.216T=0.784
1000GenomesAmericanSub694C=0.570T=0.430
1000GenomesEast AsianSub1008C=0.314T=0.686
1000GenomesEuropeSub1006C=0.572T=0.428
1000GenomesGlobalStudy-wide5008C=0.438T=0.562
1000GenomesSouth AsianSub978C=0.630T=0.370
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.557T=0.443
The Genome Aggregation DatabaseAfricanSub8696C=0.276T=0.724
The Genome Aggregation DatabaseAmericanSub830C=0.630T=0.370
The Genome Aggregation DatabaseEast AsianSub1592C=0.311T=0.689
The Genome Aggregation DatabaseEuropeSub18374C=0.527T=0.472
The Genome Aggregation DatabaseGlobalStudy-wide29794C=0.445T=0.554
The Genome Aggregation DatabaseOtherSub302C=0.580T=0.420
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.429T=0.570
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.527T=0.473
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs41328060.000105alcohol dependence24277619

eQTL of rs4132806 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4132806 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.