rs4144931

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
C==0150 (4506/29952,GnomAD)
C==0114 (3331/29118,TOPMED)
C==0079 (396/5008,1000G)
C==0230 (887/3854,ALSPAC)
C==0230 (851/3708,TWINSUK)
chr9:25658152 (GRCh38.p7) (9p21.2)
AD
GWASdb2
1   publication(s)
See rs on genome
3 Enhancers around
9 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 9NC_000009.12:g.25658152C>T
GRCh37.p13 chr 9NC_000009.11:g.25658150C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.014T=0.986
1000GenomesAmericanSub694C=0.100T=0.900
1000GenomesEast AsianSub1008C=0.001T=0.999
1000GenomesEuropeSub1006C=0.220T=0.780
1000GenomesGlobalStudy-wide5008C=0.079T=0.921
1000GenomesSouth AsianSub978C=0.090T=0.910
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.230T=0.770
The Genome Aggregation DatabaseAfricanSub8732C=0.034T=0.966
The Genome Aggregation DatabaseAmericanSub838C=0.110T=0.890
The Genome Aggregation DatabaseEast AsianSub1622C=0.001T=0.999
The Genome Aggregation DatabaseEuropeSub18458C=0.220T=0.779
The Genome Aggregation DatabaseGlobalStudy-wide29952C=0.150T=0.849
The Genome Aggregation DatabaseOtherSub302C=0.130T=0.870
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.114T=0.885
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.230T=0.770
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs41449310.00077alcohol dependence20201924

eQTL of rs4144931 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4144931 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr92567574625675889E07017596
chr92567591925676279E07017769
chr92570051725701183E07142367


Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr92567704725679488E06718897
chr92567704725679488E06818897
chr92567704725679488E06918897
chr92567704725679488E07018897
chr92567704725679488E07118897
chr92567704725679488E07218897
chr92567704725679488E07318897
chr92567704725679488E07418897
chr92567704725679488E08218897