rs42283

Homo sapiens
G>A
STARD4-AS1 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
G==0307 (9204/29936,GnomAD)
G==0324 (9459/29118,TOPMED)
G==0303 (1515/5008,1000G)
G==0369 (1424/3854,ALSPAC)
G==0366 (1357/3708,TWINSUK)
chr5:111704625 (GRCh38.p7) (5q22.1)
AD
GWASdb2
1   publication(s)
See rs on genome
111 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.111704625G>A
GRCh37.p13 chr 5NC_000005.9:g.111040322G>A

Gene: STARD4-AS1, STARD4 antisense RNA 1(plus strand)

Molecule type Change Amino acid[Codon] SO Term
STARD4-AS1 transcriptNR_040093.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.244A=0.756
1000GenomesAmericanSub694G=0.350A=0.650
1000GenomesEast AsianSub1008G=0.216A=0.784
1000GenomesEuropeSub1006G=0.384A=0.616
1000GenomesGlobalStudy-wide5008G=0.303A=0.697
1000GenomesSouth AsianSub978G=0.350A=0.650
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.369A=0.631
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.324A=0.675
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.366A=0.634
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs422830.000578alcohol dependence24277619

eQTL of rs42283 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs42283 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr5111083687111083731E06743365
chr5111083914111084391E06743592
chr5111084607111084657E06744285
chr5111084723111084890E06744401
chr5111084966111085145E06744644
chr5111085155111085264E06744833
chr5111085364111085581E06745042
chr5111018277111019066E068-21256
chr5111032574111033471E068-6851
chr5111033691111033774E068-6548
chr5111083914111084391E06843592
chr5111004496111004717E069-35605
chr5111004853111004933E069-35389
chr5111018277111019066E069-21256
chr5111032574111033471E069-6851
chr5111077965111078944E06937643
chr5111004496111004717E070-35605
chr5111004853111004933E070-35389
chr5111016295111018187E070-22135
chr5111071227111071981E07030905
chr5111072040111072096E07031718
chr5111072211111072328E07031889
chr5111072495111072653E07032173
chr5111073865111074254E07033543
chr5111074446111074603E07034124
chr5111074849111075348E07034527
chr5111076970111077366E07036648
chr5111077431111077497E07037109
chr5111077500111077837E07037178
chr5111077965111078944E07037643
chr5111078953111079132E07038631
chr5111079296111079538E07038974
chr5111079723111080002E07039401
chr5111080292111080440E07039970
chr5111080519111080642E07040197
chr5111080976111081060E07040654
chr5111081135111081277E07040813
chr5111082516111082872E07042194
chr5111082930111083099E07042608
chr5111083132111083395E07042810
chr5111083535111083600E07043213
chr5111084607111084657E07044285
chr5111084723111084890E07044401
chr5111084966111085145E07044644
chr5111085155111085264E07044833
chr5111018277111019066E071-21256
chr5111032574111033471E071-6851
chr5111077965111078944E07137643
chr5111004496111004717E072-35605
chr5111004853111004933E072-35389
chr5111077431111077497E07237109
chr5111077500111077837E07237178
chr5111077965111078944E07237643
chr5111085155111085264E07244833
chr5111085364111085581E07245042
chr5111088421111088522E07348099
chr5111004496111004717E074-35605
chr5111004853111004933E074-35389
chr5111016295111018187E081-22135
chr5111018277111019066E081-21256
chr5111032574111033471E081-6851
chr5111035837111036057E081-4265
chr5111036127111036289E081-4033
chr5111036920111036991E081-3331
chr5111071227111071981E08130905
chr5111072040111072096E08131718
chr5111072211111072328E08131889
chr5111077431111077497E08137109
chr5111077500111077837E08137178
chr5111077965111078944E08137643
chr5111078953111079132E08138631
chr5111079723111080002E08139401
chr5111080292111080440E08139970
chr5111080519111080642E08140197
chr5111082227111082277E08141905
chr5111082516111082872E08142194
chr5111082930111083099E08142608
chr5111083132111083395E08142810
chr5111083535111083600E08143213
chr5111083687111083731E08143365
chr5111083914111084391E08143592
chr5111084607111084657E08144285
chr5111084723111084890E08144401
chr5111084966111085145E08144644
chr5111085155111085264E08144833
chr5111085364111085581E08145042
chr5111086225111086603E08145903
chr5111016295111018187E082-22135
chr5111018277111019066E082-21256
chr5111071227111071981E08230905
chr5111072040111072096E08231718
chr5111072211111072328E08231889
chr5111072495111072653E08232173
chr5111076970111077366E08236648
chr5111077431111077497E08237109
chr5111077500111077837E08237178
chr5111079723111080002E08239401
chr5111080292111080440E08239970
chr5111080519111080642E08240197
chr5111080976111081060E08240654
chr5111081135111081277E08240813
chr5111081421111081471E08241099
chr5111082227111082277E08241905
chr5111082516111082872E08242194
chr5111082930111083099E08242608
chr5111083132111083395E08242810
chr5111083535111083600E08243213
chr5111083687111083731E08243365
chr5111083914111084391E08243592
chr5111084607111084657E08244285
chr5111084723111084890E08244401