SNP Detail Info-rs4235984

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A==0452 (13522/29880,GnomAD)
G=0485 (14124/29118,TOPMED)
A==0414 (2071/5008,1000G)
A==0396 (1527/3854,ALSPAC)
A==0388 (1440/3708,TWINSUK)

Position: chr6:67028168 (GRCh38.p7) (6q12)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 6	NC_000006.12:g.67028168A>G
GRCh37.p13 chr 6	NC_000006.11:g.67738061A>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.713	G=0.287
1000Genomes	American	Sub	694	A=0.340	G=0.660
1000Genomes	East Asian	Sub	1008	A=0.167	G=0.833
1000Genomes	Europe	Sub	1006	A=0.402	G=0.598
1000Genomes	Global	Study-wide	5008	A=0.414	G=0.586
1000Genomes	South Asian	Sub	978	A=0.330	G=0.670
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.396	G=0.604
The Genome Aggregation Database	African	Sub	8688	A=0.680	G=0.320
The Genome Aggregation Database	American	Sub	836	A=0.310	G=0.690
The Genome Aggregation Database	East Asian	Sub	1614	A=0.144	G=0.856
The Genome Aggregation Database	Europe	Sub	18440	A=0.378	G=0.622
The Genome Aggregation Database	Global	Study-wide	29880	A=0.452	G=0.547
The Genome Aggregation Database	Other	Sub	302	A=0.490	G=0.510
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.514	G=0.485
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.388	G=0.612

PMID	Title	Author	Journal
24277619	ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.	Quillen EE	Am J Med Genet B Neuropsychiatr Genet

SNP ID	p-value	Traits	Study
rs4235984	0.000152	alcohol consumption (maxi-drinks)	24277619

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs4235984