rs4235984

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
A==0452 (13522/29880,GnomAD)
G=0485 (14124/29118,TOPMED)
A==0414 (2071/5008,1000G)
A==0396 (1527/3854,ALSPAC)
A==0388 (1440/3708,TWINSUK)
chr6:67028168 (GRCh38.p7) (6q12)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.67028168A>G
GRCh37.p13 chr 6NC_000006.11:g.67738061A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.713G=0.287
1000GenomesAmericanSub694A=0.340G=0.660
1000GenomesEast AsianSub1008A=0.167G=0.833
1000GenomesEuropeSub1006A=0.402G=0.598
1000GenomesGlobalStudy-wide5008A=0.414G=0.586
1000GenomesSouth AsianSub978A=0.330G=0.670
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.396G=0.604
The Genome Aggregation DatabaseAfricanSub8688A=0.680G=0.320
The Genome Aggregation DatabaseAmericanSub836A=0.310G=0.690
The Genome Aggregation DatabaseEast AsianSub1614A=0.144G=0.856
The Genome Aggregation DatabaseEuropeSub18440A=0.378G=0.622
The Genome Aggregation DatabaseGlobalStudy-wide29880A=0.452G=0.547
The Genome Aggregation DatabaseOtherSub302A=0.490G=0.510
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.514G=0.485
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.388G=0.612
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs42359840.000152alcohol consumption (maxi-drinks)24277619

eQTL of rs4235984 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4235984 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.