rs4236064

Homo sapiens
G>T
KIF6 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0300 (9002/29918,GnomAD)
T=0356 (10369/29118,TOPMED)
T=0322 (1613/5008,1000G)
T=0202 (779/3854,ALSPAC)
T=0194 (720/3708,TWINSUK)
chr6:39446251 (GRCh38.p7) (6p21.2)
AD
GWASdb2
2   publication(s)
See rs on genome
110 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.39446251G>T
GRCh37.p13 chr 6NC_000006.11:g.39414027G>T

Gene: KIF6, kinesin family member 6(minus strand)

Molecule type Change Amino acid[Codon] SO Term
KIF6 transcript variant 2NM_001289020.1:c.N/AIntron Variant
KIF6 transcript variant 3NM_001289021.1:c.N/AIntron Variant
KIF6 transcript variant 1NM_145027.4:c.N/AIntron Variant
KIF6 transcript variant 4NM_001289024.1:c.N/AGenic Upstream Transcript Variant
KIF6 transcript variant X1XM_005248904.4:c.N/AIntron Variant
KIF6 transcript variant X2XM_011514357.2:c.N/AIntron Variant
KIF6 transcript variant X3XM_011514358.2:c.N/AIntron Variant
KIF6 transcript variant X4XM_011514359.2:c.N/AIntron Variant
KIF6 transcript variant X5XM_017010427.1:c.N/AIntron Variant
KIF6 transcript variant X6XM_017010428.1:c.N/AIntron Variant
KIF6 transcript variant X8XM_011514361.2:c.N/AGenic Downstream Transcript Variant
KIF6 transcript variant X7XR_001743238.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.373T=0.627
1000GenomesAmericanSub694G=0.750T=0.250
1000GenomesEast AsianSub1008G=0.751T=0.249
1000GenomesEuropeSub1006G=0.788T=0.212
1000GenomesGlobalStudy-wide5008G=0.678T=0.322
1000GenomesSouth AsianSub978G=0.850T=0.150
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.798T=0.202
The Genome Aggregation DatabaseAfricanSub8692G=0.466T=0.534
The Genome Aggregation DatabaseAmericanSub834G=0.700T=0.300
The Genome Aggregation DatabaseEast AsianSub1618G=0.743T=0.257
The Genome Aggregation DatabaseEuropeSub18472G=0.802T=0.197
The Genome Aggregation DatabaseGlobalStudy-wide29918G=0.699T=0.300
The Genome Aggregation DatabaseOtherSub302G=0.870T=0.130
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.643T=0.356
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.806T=0.194
PMID Title Author Journal
21529783A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.Heath ACBiol Psychiatry
19197363A genome-wide investigation of SNPs and CNVs in schizophrenia.Need ACPLoS Genet

P-Value

SNP ID p-value Traits Study
rs42360644.1E-05alcoholism (heaviness of drinking)21529783

eQTL of rs4236064 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4236064 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr63936961739369697E067-44330
chr63937925839379545E067-34482
chr63938770239387779E067-26248
chr63939363639394215E067-19812
chr63939423839394385E067-19642
chr63939931839399454E067-14573
chr63939996339400681E067-13346
chr63945618439456275E06742157
chr63936998439370386E068-43641
chr63937925839379545E068-34482
chr63938386739384159E068-29868
chr63938417839385006E068-29021
chr63939015339390379E068-23648
chr63939315939393423E068-20604
chr63939363639394215E068-19812
chr63939423839394385E068-19642
chr63939466939394793E068-19234
chr63939931839399454E068-14573
chr63936406139364135E069-49892
chr63936463039364680E069-49347
chr63936944939369551E069-44476
chr63936961739369697E069-44330
chr63936998439370386E069-43641
chr63937103139371115E069-42912
chr63937117439371279E069-42748
chr63937925839379545E069-34482
chr63938386739384159E069-29868
chr63938417839385006E069-29021
chr63938508039385295E069-28732
chr63938536039385452E069-28575
chr63938819439388352E069-25675
chr63939363639394215E069-19812
chr63939423839394385E069-19642
chr63939466939394793E069-19234
chr63939489339395073E069-18954
chr63939790639398754E069-15273
chr63939996339400681E069-13346
chr63945618439456275E06942157
chr63936961739369697E071-44330
chr63936998439370386E071-43641
chr63937103139371115E071-42912
chr63937117439371279E071-42748
chr63937925839379545E071-34482
chr63938386739384159E071-29868
chr63938417839385006E071-29021
chr63938925439389559E071-24468
chr63938972639389865E071-24162
chr63939015339390379E071-23648
chr63939363639394215E071-19812
chr63939423839394385E071-19642
chr63945618439456275E07142157
chr63936406139364135E072-49892
chr63936463039364680E072-49347
chr63936864139368855E072-45172
chr63936944939369551E072-44476
chr63936961739369697E072-44330
chr63936998439370386E072-43641
chr63937103139371115E072-42912
chr63937117439371279E072-42748
chr63937925839379545E072-34482
chr63938386739384159E072-29868
chr63938417839385006E072-29021
chr63938753039387637E072-26390
chr63938770239387779E072-26248
chr63938819439388352E072-25675
chr63938925439389559E072-24468
chr63938972639389865E072-24162
chr63939315939393423E072-20604
chr63939363639394215E072-19812
chr63939423839394385E072-19642
chr63939996339400681E072-13346
chr63937925839379545E073-34482
chr63938386739384159E073-29868
chr63938417839385006E073-29021
chr63939363639394215E073-19812
chr63939466939394793E073-19234
chr63939790639398754E073-15273
chr63939876739399280E073-14747
chr63936864139368855E074-45172
chr63936944939369551E074-44476
chr63936961739369697E074-44330
chr63936998439370386E074-43641
chr63937103139371115E074-42912
chr63937117439371279E074-42748
chr63937925839379545E074-34482
chr63938386739384159E074-29868
chr63938417839385006E074-29021
chr63938508039385295E074-28732
chr63938536039385452E074-28575
chr63938925439389559E074-24468
chr63938972639389865E074-24162
chr63939363639394215E074-19812
chr63939423839394385E074-19642
chr63939466939394793E074-19234
chr63939489339395073E074-18954
chr63939592739396402E074-17625
chr63939656739396647E074-17380
chr63939668439396754E074-17273
chr63939790639398754E074-15273
chr63939996339400681E074-13346
chr63938536039385452E081-28575
chr63939876739399280E081-14747
chr63939931839399454E081-14573
chr63936406139364135E082-49892
chr63938338439383453E082-30574
chr63938386739384159E082-29868
chr63938417839385006E082-29021
chr63938508039385295E082-28732
chr63939876739399280E082-14747
chr63939931839399454E082-14573