rs4245803

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0201 (6030/29918,GnomAD)
A=0167 (4874/29116,TOPMED)
A=0255 (1276/5008,1000G)
A=0223 (861/3854,ALSPAC)
A=0214 (793/3708,TWINSUK)
chr2:45347067 (GRCh38.p7) (2p21)
AD
GWASdb2
1   publication(s)
See rs on genome
9 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.45347067G>A
GRCh37.p13 chr 2NC_000002.11:g.45574206G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.958A=0.042
1000GenomesAmericanSub694G=0.780A=0.220
1000GenomesEast AsianSub1008G=0.449A=0.551
1000GenomesEuropeSub1006G=0.777A=0.223
1000GenomesGlobalStudy-wide5008G=0.745A=0.255
1000GenomesSouth AsianSub978G=0.710A=0.290
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.777A=0.223
The Genome Aggregation DatabaseAfricanSub8712G=0.924A=0.076
The Genome Aggregation DatabaseAmericanSub834G=0.750A=0.250
The Genome Aggregation DatabaseEast AsianSub1604G=0.390A=0.610
The Genome Aggregation DatabaseEuropeSub18466G=0.778A=0.222
The Genome Aggregation DatabaseGlobalStudy-wide29918G=0.798A=0.201
The Genome Aggregation DatabaseOtherSub302G=0.750A=0.250
Trans-Omics for Precision MedicineGlobalStudy-wide29116G=0.832A=0.167
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.786A=0.214
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs42458030.00043alcohol dependence20201924

eQTL of rs4245803 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4245803 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr24552726345527492E070-46714
chr24552852545528791E070-45415
chr24552883645529012E070-45194
chr24552909545529327E070-44879
chr24557965845579708E0705452
chr24557979645580031E0705590
chr24558003745580146E0705831
chr24558072945580802E0706523
chr24558093845581483E0706732