rs4268066

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
C==0129 (3885/29962,GnomAD)
C==0180 (5246/29118,TOPMED)
C==0145 (725/5008,1000G)
C==0079 (304/3854,ALSPAC)
C==0077 (284/3708,TWINSUK)
chr7:118961051 (GRCh38.p7) (7q31.31)
AD
GWASdb2
1   publication(s)
See rs on genome
6 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.118961051C>T
GRCh37.p13 chr 7NC_000007.13:g.118601105C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.344T=0.656
1000GenomesAmericanSub694C=0.100T=0.900
1000GenomesEast AsianSub1008C=0.081T=0.919
1000GenomesEuropeSub1006C=0.073T=0.927
1000GenomesGlobalStudy-wide5008C=0.145T=0.855
1000GenomesSouth AsianSub978C=0.050T=0.950
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.079T=0.921
The Genome Aggregation DatabaseAfricanSub8716C=0.299T=0.701
The Genome Aggregation DatabaseAmericanSub834C=0.110T=0.890
The Genome Aggregation DatabaseEast AsianSub1616C=0.092T=0.908
The Genome Aggregation DatabaseEuropeSub18494C=0.054T=0.945
The Genome Aggregation DatabaseGlobalStudy-wide29962C=0.129T=0.870
The Genome Aggregation DatabaseOtherSub302C=0.120T=0.880
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.180T=0.819
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.077T=0.923
PMID Title Author Journal
22613542ANKRD7 and CYTL1 are novel risk genes for alcohol drinking behavior.Chen XDChin Med J (Engl)

P-Value

SNP ID p-value Traits Study
rs42680663.44E-07alcohol consumption22613542

eQTL of rs4268066 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4268066 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr7118614632118614702E08113527
chr7118614812118615340E08113707
chr7118639808118640007E08138703
chr7118640023118640111E08138918
chr7118646613118646739E08145508
chr7118647292118647578E08146187