rs42905

Homo sapiens
A>C
None
Check p-value
SNV (Single Nucleotide Variation)
A==0475 (14163/29796,GnomAD)
A==0472 (13760/29118,TOPMED)
A==0434 (2173/5008,1000G)
A==0457 (1761/3854,ALSPAC)
A==0437 (1619/3708,TWINSUK)
chr5:68455394 (GRCh38.p7) (5q13.1)
AD
GWASdb2
1   publication(s)
See rs on genome
36 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.68455394A>C
GRCh37.p13 chr 5NC_000005.9:g.67751221A>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.517C=0.483
1000GenomesAmericanSub694A=0.380C=0.620
1000GenomesEast AsianSub1008A=0.253C=0.747
1000GenomesEuropeSub1006A=0.430C=0.570
1000GenomesGlobalStudy-wide5008A=0.434C=0.566
1000GenomesSouth AsianSub978A=0.550C=0.450
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.457C=0.543
The Genome Aggregation DatabaseAfricanSub8672A=0.533C=0.467
The Genome Aggregation DatabaseAmericanSub834A=0.340C=0.660
The Genome Aggregation DatabaseEast AsianSub1612A=0.212C=0.788
The Genome Aggregation DatabaseEuropeSub18376A=0.478C=0.521
The Genome Aggregation DatabaseGlobalStudy-wide29796A=0.475C=0.524
The Genome Aggregation DatabaseOtherSub302A=0.440C=0.560
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.472C=0.527
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.437C=0.563
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs429050.000533alcohol dependence20201924

eQTL of rs42905 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs42905 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr56771543567716031E067-35190
chr56774061067740951E067-10270
chr56772913367729228E068-21993
chr56773703167737810E068-13411
chr56775244267752952E0681221
chr56775537467755503E0684153
chr56775597067756342E0684749
chr56772931167730778E069-20443
chr56773124067731483E069-19738
chr56773152267731732E069-19489
chr56774061067740951E069-10270
chr56775244267752952E0691221
chr56770178167701846E070-49375
chr56772074967721370E071-29851
chr56772159067721661E071-29560
chr56772913367729228E071-21993
chr56772931167730778E071-20443
chr56773124067731483E071-19738
chr56773152267731732E071-19489
chr56773178367731896E071-19325
chr56773477967735052E071-16169
chr56775244267752952E0711221
chr56775597067756342E0714749
chr56771492067715269E072-35952
chr56777513867775753E07223917
chr56770258667702963E073-48258
chr56777651367776601E07325292
chr56777853067778580E07327309
chr56770258667702963E074-48258
chr56773477967735052E074-16169
chr56775244267752952E0741221
chr56773682967736893E081-14328
chr56773692267736972E081-14249
chr56773703167737810E081-13411
chr56777651367776601E08125292
chr56773703167737810E082-13411