rs4345283

Homo sapiens
A>C
FLJ33360 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A==0374 (11201/29882,GnomAD)
A==0363 (10582/29118,TOPMED)
A==0454 (2275/5008,1000G)
A==0400 (1541/3854,ALSPAC)
A==0398 (1474/3708,TWINSUK)
chr5:6325737 (GRCh38.p7) (5p15.31)
AD
GWASdb2
1   publication(s)
See rs on genome
25 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.6325737A>C
GRCh37.p13 chr 5NC_000005.9:g.6325850A>C

Gene: FLJ33360, FLJ33360 protein(minus strand)

Molecule type Change Amino acid[Codon] SO Term
LINC02145 transcriptNR_028351.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.275C=0.725
1000GenomesAmericanSub694A=0.550C=0.450
1000GenomesEast AsianSub1008A=0.656C=0.344
1000GenomesEuropeSub1006A=0.396C=0.604
1000GenomesGlobalStudy-wide5008A=0.454C=0.546
1000GenomesSouth AsianSub978A=0.480C=0.520
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.400C=0.600
The Genome Aggregation DatabaseAfricanSub8686A=0.297C=0.703
The Genome Aggregation DatabaseAmericanSub836A=0.560C=0.440
The Genome Aggregation DatabaseEast AsianSub1618A=0.635C=0.365
The Genome Aggregation DatabaseEuropeSub18442A=0.378C=0.621
The Genome Aggregation DatabaseGlobalStudy-wide29882A=0.374C=0.625
The Genome Aggregation DatabaseOtherSub300A=0.440C=0.560
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.363C=0.636
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.398C=0.602
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs43452830.000822alcohol dependence20201924

eQTL of rs4345283 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4345283 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr563335896333855E0677739
chr563335896333855E0687739
chr563335896333855E0697739
chr562874116287497E070-38353
chr563021606302551E070-23299
chr563027446302860E070-22990
chr563196606319710E070-6140
chr563200606320189E070-5661
chr563383946338504E07012544
chr563389406339014E07013090
chr563392506339300E07013400
chr563335896333855E0717739
chr563335896333855E0737739
chr563605736360702E07334723
chr563335896333855E0747739
chr562764026276790E081-49060
chr562815356281601E081-44249
chr563174576317749E081-8101
chr563178696318069E081-7781
chr562764026276790E082-49060
chr563071266307230E082-18620
chr563174576317749E082-8101
chr563178696318069E082-7781
chr563194366319565E082-6285
chr563196606319710E082-6140