rs4349529

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
A==0498 (14849/29810,GnomAD)
G=0453 (13209/29118,TOPMED)
A==0428 (2143/5008,1000G)
A==0467 (1799/3854,ALSPAC)
A==0469 (1740/3708,TWINSUK)
chr3:17750626 (GRCh38.p7) (3p24.3)
AD
GWASdb2
1   publication(s)
See rs on genome
29 Enhancers around
10 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.17750626A>G
GRCh37.p13 chr 3NC_000003.11:g.17792118A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.733G=0.267
1000GenomesAmericanSub694A=0.370G=0.630
1000GenomesEast AsianSub1008A=0.069G=0.931
1000GenomesEuropeSub1006A=0.473G=0.527
1000GenomesGlobalStudy-wide5008A=0.428G=0.572
1000GenomesSouth AsianSub978A=0.380G=0.620
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.467G=0.533
The Genome Aggregation DatabaseAfricanSub8688A=0.679G=0.321
The Genome Aggregation DatabaseAmericanSub824A=0.280G=0.720
The Genome Aggregation DatabaseEast AsianSub1616A=0.043G=0.957
The Genome Aggregation DatabaseEuropeSub18380A=0.463G=0.536
The Genome Aggregation DatabaseGlobalStudy-wide29810A=0.498G=0.501
The Genome Aggregation DatabaseOtherSub302A=0.420G=0.580
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.546G=0.453
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.469G=0.531
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs43495290.000568alcohol dependence20201924

eQTL of rs4349529 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4349529 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr31777177817771886E067-20232
chr31777195517772104E067-20014
chr31777216817772239E067-19879
chr31777310917773159E067-18959
chr31778058917780671E067-11447
chr31778070317780808E067-11310
chr31784089617841144E06748778
chr31784184717842072E06749729
chr31778058917780671E068-11447
chr31778070317780808E068-11310
chr31778698417787044E068-5074
chr31779489717795061E0682779
chr31779513717795498E0683019
chr31784089617841144E06848778
chr31784184717842072E06849729
chr31778698417787044E069-5074
chr31784089617841144E06948778
chr31780152417801746E0719406
chr31784089617841144E07148778
chr31778698417787044E072-5074
chr31779461217794870E0722494
chr31779489717795061E0722779
chr31779513717795498E0723019
chr31780152417801746E0729406
chr31784089617841144E07248778
chr31784184717842072E07249729
chr31784089617841144E07348778
chr31778698417787044E074-5074
chr31784184717842072E07449729







Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr31778211517785004E067-7114
chr31778211517785004E068-7114
chr31778211517785004E069-7114
chr31778211517785004E070-7114
chr31778211517785004E071-7114
chr31778211517785004E072-7114
chr31778211517785004E073-7114
chr31778211517785004E074-7114
chr31778211517785004E081-7114
chr31778211517785004E082-7114