rs4370037

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0392 (11705/29804,GnomAD)
A=0454 (13230/29118,TOPMED)
A=0437 (2189/5008,1000G)
A=0304 (1173/3854,ALSPAC)
A=0302 (1121/3708,TWINSUK)
chr3:103703268 (GRCh38.p7) (3q13.11)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.103703268G>A
GRCh37.p13 chr 3NC_000003.11:g.103422112G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.349A=0.651
1000GenomesAmericanSub694G=0.610A=0.390
1000GenomesEast AsianSub1008G=0.649A=0.351
1000GenomesEuropeSub1006G=0.682A=0.318
1000GenomesGlobalStudy-wide5008G=0.563A=0.437
1000GenomesSouth AsianSub978G=0.610A=0.390
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.696A=0.304
The Genome Aggregation DatabaseAfricanSub8702G=0.396A=0.604
The Genome Aggregation DatabaseAmericanSub830G=0.600A=0.400
The Genome Aggregation DatabaseEast AsianSub1576G=0.656A=0.344
The Genome Aggregation DatabaseEuropeSub18394G=0.703A=0.296
The Genome Aggregation DatabaseGlobalStudy-wide29804G=0.607A=0.392
The Genome Aggregation DatabaseOtherSub302G=0.610A=0.390
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.545A=0.454
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.698A=0.302
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs43700370.000126alcohol consumption (maxi-drinks)24277619

eQTL of rs4370037 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4370037 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.