SNP Detail Info-rs4370037

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0392 (11705/29804,GnomAD)
A=0454 (13230/29118,TOPMED)
A=0437 (2189/5008,1000G)
A=0304 (1173/3854,ALSPAC)
A=0302 (1121/3708,TWINSUK)

Position: chr3:103703268 (GRCh38.p7) (3q13.11)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 3	NC_000003.12:g.103703268G>A
GRCh37.p13 chr 3	NC_000003.11:g.103422112G>A

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.349	A=0.651
1000Genomes	American	Sub	694	G=0.610	A=0.390
1000Genomes	East Asian	Sub	1008	G=0.649	A=0.351
1000Genomes	Europe	Sub	1006	G=0.682	A=0.318
1000Genomes	Global	Study-wide	5008	G=0.563	A=0.437
1000Genomes	South Asian	Sub	978	G=0.610	A=0.390
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.696	A=0.304
The Genome Aggregation Database	African	Sub	8702	G=0.396	A=0.604
The Genome Aggregation Database	American	Sub	830	G=0.600	A=0.400
The Genome Aggregation Database	East Asian	Sub	1576	G=0.656	A=0.344
The Genome Aggregation Database	Europe	Sub	18394	G=0.703	A=0.296
The Genome Aggregation Database	Global	Study-wide	29804	G=0.607	A=0.392
The Genome Aggregation Database	Other	Sub	302	G=0.610	A=0.390
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.545	A=0.454
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.698	A=0.302

PMID	Title	Author	Journal
24277619	ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.	Quillen EE	Am J Med Genet B Neuropsychiatr Genet

SNP ID	p-value	Traits	Study
rs4370037	0.000126	alcohol consumption (maxi-drinks)	24277619

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs4370037