rs4407211

Homo sapiens
T>C
LOC107985953 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T==0087 (2605/29942,GnomAD)
T==0116 (3380/29118,TOPMED)
T==0089 (444/5008,1000G)
T==0030 (115/3854,ALSPAC)
T==0035 (129/3708,TWINSUK)
chr2:155650004 (GRCh38.p7) (2q24.1)
AD
GWASdb2
1   publication(s)
See rs on genome
11 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.155650004T>C
GRCh37.p13 chr 2NC_000002.11:g.156506516T>C

Gene: LOC107985953, uncharacterized LOC107985953(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC107985953 transcript variant X1XR_001739746.1:n.N/AIntron Variant
LOC107985953 transcript variant X2XR_001739747.1:n.N/AIntron Variant
LOC107985953 transcript variant X3XR_001739748.1:n.N/AGenic Downstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.261C=0.739
1000GenomesAmericanSub694T=0.040C=0.960
1000GenomesEast AsianSub1008T=0.020C=0.980
1000GenomesEuropeSub1006T=0.017C=0.983
1000GenomesGlobalStudy-wide5008T=0.089C=0.911
1000GenomesSouth AsianSub978T=0.030C=0.970
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.030C=0.970
The Genome Aggregation DatabaseAfricanSub8706T=0.232C=0.768
The Genome Aggregation DatabaseAmericanSub836T=0.030C=0.970
The Genome Aggregation DatabaseEast AsianSub1618T=0.018C=0.982
The Genome Aggregation DatabaseEuropeSub18480T=0.028C=0.971
The Genome Aggregation DatabaseGlobalStudy-wide29942T=0.087C=0.913
The Genome Aggregation DatabaseOtherSub302T=0.010C=0.990
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.116C=0.883
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.035C=0.965
PMID Title Author Journal
23953852Genome-wide association studies of maximum number of drinks.Pan YJ Psychiatr Res

P-Value

SNP ID p-value Traits Study
rs44072113.24E-06alcohol consumption23953852

eQTL of rs4407211 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4407211 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr2156547477156547564E06840961
chr2156547580156547696E06841064
chr2156545853156546995E06939337
chr2156547091156547260E06940575
chr2156547477156547564E06940961
chr2156547580156547696E06941064
chr2156545853156546995E07139337
chr2156547091156547260E07140575
chr2156547477156547564E07140961
chr2156547580156547696E07141064
chr2156548664156548911E07442148