SNP Detail Info-rs4421732

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A==0217 (6518/29906,GnomAD)
A==0201 (5863/29118,TOPMED)
A==0284 (1423/5008,1000G)
A==0201 (773/3854,ALSPAC)
A==0190 (703/3708,TWINSUK)

Position: chr11:42678122 (GRCh38.p7) (11p12)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 2 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 11	NC_000011.10:g.42678122A>G
GRCh37.p13 chr 11	NC_000011.9:g.42699672A>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.233	G=0.767
1000Genomes	American	Sub	694	A=0.190	G=0.810
1000Genomes	East Asian	Sub	1008	A=0.542	G=0.458
1000Genomes	Europe	Sub	1006	A=0.172	G=0.828
1000Genomes	Global	Study-wide	5008	A=0.284	G=0.716
1000Genomes	South Asian	Sub	978	A=0.270	G=0.730
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.201	G=0.799
The Genome Aggregation Database	African	Sub	8700	A=0.217	G=0.783
The Genome Aggregation Database	American	Sub	836	A=0.230	G=0.770
The Genome Aggregation Database	East Asian	Sub	1586	A=0.555	G=0.445
The Genome Aggregation Database	Europe	Sub	18482	A=0.190	G=0.809
The Genome Aggregation Database	Global	Study-wide	29906	A=0.217	G=0.782
The Genome Aggregation Database	Other	Sub	302	A=0.130	G=0.870
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.201	G=0.798
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.190	G=0.810

PMID	Title	Author	Journal
23953852	Genome-wide association studies of maximum number of drinks.	Pan Y	J Psychiatr Res

SNP ID	p-value	Traits	Study
rs4421732	2.44E-05	alcohol consumption	23953852

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr11	42678532	42679078	E082	-20594
chr11	42679191	42679381	E082	-20291

rs4421732