rs442555

Homo sapiens
T>C
LINC01500 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0127 (3802/29932,GnomAD)
C=0132 (3843/29118,TOPMED)
C=0089 (446/5008,1000G)
C=0117 (450/3854,ALSPAC)
C=0124 (460/3708,TWINSUK)
chr14:58829466 (GRCh38.p7) (14q23.1)
AD
GWASdb2
1   publication(s)
See rs on genome
221 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 14NC_000014.9:g.58829466T>C
GRCh37.p13 chr 14NC_000014.8:g.59296184T>C

Gene: LINC01500, long intergenic non-protein coding RNA 1500(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LINC01500 transcriptNR_110547.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.856C=0.144
1000GenomesAmericanSub694T=0.940C=0.060
1000GenomesEast AsianSub1008T=0.984C=0.016
1000GenomesEuropeSub1006T=0.879C=0.121
1000GenomesGlobalStudy-wide5008T=0.911C=0.089
1000GenomesSouth AsianSub978T=0.930C=0.070
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.883C=0.117
The Genome Aggregation DatabaseAfricanSub8696T=0.841C=0.159
The Genome Aggregation DatabaseAmericanSub836T=0.940C=0.060
The Genome Aggregation DatabaseEast AsianSub1620T=0.990C=0.010
The Genome Aggregation DatabaseEuropeSub18478T=0.873C=0.126
The Genome Aggregation DatabaseGlobalStudy-wide29932T=0.873C=0.127
The Genome Aggregation DatabaseOtherSub302T=0.920C=0.080
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.868C=0.132
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.876C=0.124
PMID Title Author Journal
21529783A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.Heath ACBiol Psychiatry

P-Value

SNP ID p-value Traits Study
rs4425559.8E-05alcoholism (heaviness of drinking)21529783

eQTL of rs442555 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs442555 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr145925281859252961E067-43223
chr145925298959253378E067-42806
chr145925388359253933E067-42251
chr145925419159254241E067-41943
chr145925427259254346E067-41838
chr145925442559254625E067-41559
chr145925472759254777E067-41407
chr145925509959255190E067-40994
chr145925524459255362E067-40822
chr145925543059256169E067-40015
chr145925633159256385E067-39799
chr145925643259256498E067-39686
chr145925654259256772E067-39412
chr145927480459274875E067-21309
chr145927501059275089E067-21095
chr145927537359275541E067-20643
chr145927558859275926E067-20258
chr145927838259278462E067-17722
chr145927850159278551E067-17633
chr145927882659279729E067-16455
chr145928183859282990E067-13194
chr145929083559291402E067-4782
chr145929153859291618E067-4566
chr145925419159254241E068-41943
chr145925427259254346E068-41838
chr145925442559254625E068-41559
chr145925472759254777E068-41407
chr145925509959255190E068-40994
chr145925524459255362E068-40822
chr145925543059256169E068-40015
chr145925633159256385E068-39799
chr145929083559291402E068-4782
chr145925419159254241E069-41943
chr145925427259254346E069-41838
chr145925442559254625E069-41559
chr145925472759254777E069-41407
chr145925509959255190E069-40994
chr145925524459255362E069-40822
chr145925543059256169E069-40015
chr145925633159256385E069-39799
chr145925643259256498E069-39686
chr145925654259256772E069-39412
chr145925684359256927E069-39257
chr145925698259257229E069-38955
chr145928183859282990E069-13194
chr145928310559283517E069-12667
chr145928352459283964E069-12220
chr145929083559291402E069-4782
chr145929153859291618E069-4566
chr145929165959291755E069-4429
chr145924909359249133E070-47051
chr145924913559249185E070-46999
chr145925031759250551E070-45633
chr145925061359250839E070-45345
chr145925095159251027E070-45157
chr145925116759251354E070-44830
chr145925150059251550E070-44634
chr145925159259251659E070-44525
chr145925178759251912E070-44272
chr145925509959255190E070-40994
chr145925524459255362E070-40822
chr145927155859272170E070-24014
chr145927217159272373E070-23811
chr145927602459276088E070-20096
chr145928183859282990E070-13194
chr145929867359299359E0702489
chr145929937959299508E0703195
chr145930712859307363E07010944
chr145930738959308086E07011205
chr145930874859308798E07012564
chr145925419159254241E071-41943
chr145925427259254346E071-41838
chr145925442559254625E071-41559
chr145925472759254777E071-41407
chr145925509959255190E071-40994
chr145925524459255362E071-40822
chr145925543059256169E071-40015
chr145925633159256385E071-39799
chr145925643259256498E071-39686
chr145925654259256772E071-39412
chr145927501059275089E071-21095
chr145927537359275541E071-20643
chr145927558859275926E071-20258
chr145927602459276088E071-20096
chr145928183859282990E071-13194
chr145928310559283517E071-12667
chr145925281859252961E072-43223
chr145925298959253378E072-42806
chr145925419159254241E072-41943
chr145925427259254346E072-41838
chr145925442559254625E072-41559
chr145925472759254777E072-41407
chr145925509959255190E072-40994
chr145925524459255362E072-40822
chr145925543059256169E072-40015
chr145925633159256385E072-39799
chr145925643259256498E072-39686
chr145925654259256772E072-39412
chr145927784759277911E072-18273
chr145927800859278136E072-18048
chr145927818859278238E072-17946
chr145927838259278462E072-17722
chr145927850159278551E072-17633
chr145928129659281705E072-14479
chr145928183859282990E072-13194
chr145928310559283517E072-12667
chr145928352459283964E072-12220
chr145928568659285794E072-10390
chr145928625259286332E072-9852
chr145929083559291402E072-4782
chr145929153859291618E072-4566
chr145929867359299359E0722489
chr145929937959299508E0723195
chr145925281859252961E073-43223
chr145925419159254241E073-41943
chr145925427259254346E073-41838
chr145925442559254625E073-41559
chr145925472759254777E073-41407
chr145925509959255190E073-40994
chr145925524459255362E073-40822
chr145925543059256169E073-40015
chr145925633159256385E073-39799
chr145927882659279729E073-16455
chr145928310559283517E073-12667
chr145928352459283964E073-12220
chr145929867359299359E0732489
chr145929937959299508E0733195
chr145925419159254241E074-41943
chr145925427259254346E074-41838
chr145925442559254625E074-41559
chr145925472759254777E074-41407
chr145925509959255190E074-40994
chr145925524459255362E074-40822
chr145925543059256169E074-40015
chr145925633159256385E074-39799
chr145925643259256498E074-39686
chr145925654259256772E074-39412
chr145925724759257297E074-38887
chr145927480459274875E074-21309
chr145927501059275089E074-21095
chr145927537359275541E074-20643
chr145927558859275926E074-20258
chr145927602459276088E074-20096
chr145928183859282990E074-13194
chr145928310559283517E074-12667
chr145929083559291402E074-4782
chr145929867359299359E0742489
chr145924698359247187E081-48997
chr145924734559247703E081-48481
chr145925150059251550E081-44634
chr145925159259251659E081-44525
chr145925178759251912E081-44272
chr145925196059252167E081-44017
chr145925232359252804E081-43380
chr145925281859252961E081-43223
chr145925298959253378E081-42806
chr145925388359253933E081-42251
chr145925419159254241E081-41943
chr145925427259254346E081-41838
chr145925442559254625E081-41559
chr145925472759254777E081-41407
chr145925509959255190E081-40994
chr145925524459255362E081-40822
chr145925543059256169E081-40015
chr145925633159256385E081-39799
chr145925643259256498E081-39686
chr145925654259256772E081-39412
chr145925684359256927E081-39257
chr145926499059265249E081-30935
chr145926534459265586E081-30598
chr145926565259265740E081-30444
chr145927268059273259E081-22925
chr145927800859278136E081-18048
chr145927818859278238E081-17946
chr145927838259278462E081-17722
chr145927850159278551E081-17633
chr145927882659279729E081-16455
chr145927975959279851E081-16333
chr145928004559280110E081-16074
chr145928017959280259E081-15925
chr145928310559283517E081-12667
chr145928352459283964E081-12220
chr145928454659284832E081-11352
chr145928485759284925E081-11259
chr145929867359299359E0812489
chr145929937959299508E0813195
chr145932922859329431E08133044
chr145932963359329749E08133449
chr145932983359329899E08133649
chr145933140059333452E08135216
chr145933925259339958E08143068
chr145934000759340390E08143823
chr145934039459340505E08144210
chr145934053959340649E08144355
chr145924698359247187E082-48997
chr145924734559247703E082-48481
chr145925442559254625E082-41559
chr145925472759254777E082-41407
chr145925509959255190E082-40994
chr145925524459255362E082-40822
chr145925543059256169E082-40015
chr145925633159256385E082-39799
chr145925643259256498E082-39686
chr145925654259256772E082-39412
chr145926301059263330E082-32854
chr145926341259263735E082-32449
chr145926499059265249E082-30935
chr145926534459265586E082-30598
chr145926565259265740E082-30444
chr145927800859278136E082-18048
chr145927818859278238E082-17946
chr145927838259278462E082-17722
chr145927850159278551E082-17633
chr145928062159280737E082-15447
chr145929867359299359E0822489
chr145929937959299508E0823195
chr145933140059333452E08235216
chr145933925259339958E08243068
chr145934000759340390E08243823
chr145934039459340505E08244210
chr145934053959340649E08244355