rs443394

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
C==0343 (10268/29926,GnomAD)
C==0336 (9791/29118,TOPMED)
C==0273 (1365/5008,1000G)
C==0418 (1610/3854,ALSPAC)
C==0427 (1584/3708,TWINSUK)
chr15:79741543 (GRCh38.p7) (15q25.1)
AD
GWASdb2
1   publication(s)
See rs on genome
14 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 15NC_000015.10:g.79741543C>T
GRCh37.p13 chr 15NC_000015.9:g.80033885C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.177T=0.823
1000GenomesAmericanSub694C=0.420T=0.580
1000GenomesEast AsianSub1008C=0.179T=0.821
1000GenomesEuropeSub1006C=0.401T=0.599
1000GenomesGlobalStudy-wide5008C=0.273T=0.727
1000GenomesSouth AsianSub978C=0.260T=0.740
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.418T=0.582
The Genome Aggregation DatabaseAfricanSub8714C=0.221T=0.779
The Genome Aggregation DatabaseAmericanSub836C=0.430T=0.570
The Genome Aggregation DatabaseEast AsianSub1616C=0.153T=0.847
The Genome Aggregation DatabaseEuropeSub18460C=0.413T=0.587
The Genome Aggregation DatabaseGlobalStudy-wide29926C=0.343T=0.656
The Genome Aggregation DatabaseOtherSub300C=0.350T=0.650
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.336T=0.663
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.427T=0.573
PMID Title Author Journal
23089632A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53.Wang JCMol Psychiatry

P-Value

SNP ID p-value Traits Study
rs4433944.66E-06alcohol dependence23089632

eQTL of rs443394 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs443394 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr158006241780062500E06828532
chr158003376580033815E070-70
chr158006241780062500E07028532
chr158006268480062742E07028799
chr158006277380062827E07028888
chr158006289880063027E07029013
chr158006241780062500E07228532
chr158006268480062742E07228799
chr158006277380062827E07228888
chr158006289880063027E07229013
chr158006241780062500E07428532
chr158006268480062742E07428799
chr158006277380062827E07428888
chr158006289880063027E07429013