rs4502928

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0305 (9138/29916,GnomAD)
G=0277 (8080/29118,TOPMED)
G=0423 (2120/5008,1000G)
G=0273 (1053/3854,ALSPAC)
G=0276 (1025/3708,TWINSUK)
chr6:23214002 (GRCh38.p7) (6p22.3)
AD
GWASdb2
1   publication(s)
See rs on genome
51 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.23214002A>G
GRCh37.p13 chr 6NC_000006.11:g.23214230A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.817G=0.183
1000GenomesAmericanSub694A=0.560G=0.440
1000GenomesEast AsianSub1008A=0.237G=0.763
1000GenomesEuropeSub1006A=0.679G=0.321
1000GenomesGlobalStudy-wide5008A=0.577G=0.423
1000GenomesSouth AsianSub978A=0.510G=0.490
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.727G=0.273
The Genome Aggregation DatabaseAfricanSub8712A=0.792G=0.208
The Genome Aggregation DatabaseAmericanSub838A=0.510G=0.490
The Genome Aggregation DatabaseEast AsianSub1614A=0.206G=0.794
The Genome Aggregation DatabaseEuropeSub18450A=0.700G=0.299
The Genome Aggregation DatabaseGlobalStudy-wide29916A=0.694G=0.305
The Genome Aggregation DatabaseOtherSub302A=0.680G=0.320
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.722G=0.277
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.724G=0.276
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs45029280.000863alcohol consumption (maxi-drinks)24277619

eQTL of rs4502928 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4502928 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr62318051223181526E067-32704
chr62318158223182017E067-32213
chr62321904623219273E0674816
chr62318051223181526E068-32704
chr62318158223182017E068-32213
chr62321904623219273E0684816
chr62318031023180442E069-33788
chr62318045223180502E069-33728
chr62318051223181526E069-32704
chr62317358523173816E070-40414
chr62317605223176182E070-38048
chr62317650323176633E070-37597
chr62317684023176947E070-37283
chr62317744523177600E070-36630
chr62317787023178010E070-36220
chr62317821723178286E070-35944
chr62317897223179028E070-35202
chr62317983323179905E070-34325
chr62318031023180442E070-33788
chr62318045223180502E070-33728
chr62318051223181526E070-32704
chr62318158223182017E070-32213
chr62318203023182083E070-32147
chr62318285623182948E070-31282
chr62318436423184441E070-29789
chr62318460323184953E070-29277
chr62321904623219273E0704816
chr62318051223181526E071-32704
chr62318158223182017E071-32213
chr62318203023182083E071-32147
chr62321904623219273E0714816
chr62318051223181526E072-32704
chr62318158223182017E072-32213
chr62318203023182083E072-32147
chr62321904623219273E0724816
chr62318031023180442E074-33788
chr62318045223180502E074-33728
chr62318051223181526E074-32704
chr62318158223182017E074-32213
chr62321904623219273E0744816
chr62317983323179905E081-34325
chr62318031023180442E081-33788
chr62318045223180502E081-33728
chr62318051223181526E081-32704
chr62318158223182017E081-32213
chr62318203023182083E081-32147
chr62318031023180442E082-33788
chr62318045223180502E082-33728
chr62318051223181526E082-32704
chr62318158223182017E082-32213
chr62318203023182083E082-32147