SNP Detail Info-rs4518581

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G==0179 (5239/29118,TOPMED)
G==0128 (3692/28744,GnomAD)
G==0144 (723/5008,1000G)
G==0079 (305/3854,ALSPAC)
G==0077 (286/3708,TWINSUK)

Position: chr7:118970601 (GRCh38.p7) (7q31.31)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 6 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 7	NC_000007.14:g.118970601G>A
GRCh37.p13 chr 7	NC_000007.13:g.118610655G>A

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.344	A=0.656
1000Genomes	American	Sub	694	G=0.100	A=0.900
1000Genomes	East Asian	Sub	1008	G=0.080	A=0.920
1000Genomes	Europe	Sub	1006	G=0.073	A=0.927
1000Genomes	Global	Study-wide	5008	G=0.144	A=0.856
1000Genomes	South Asian	Sub	978	G=0.050	A=0.950
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.079	A=0.921
The Genome Aggregation Database	African	Sub	8382	G=0.296	A=0.704
The Genome Aggregation Database	American	Sub	796	G=0.100	A=0.900
The Genome Aggregation Database	East Asian	Sub	1588	G=0.092	A=0.908
The Genome Aggregation Database	Europe	Sub	17678	G=0.053	A=0.946
The Genome Aggregation Database	Global	Study-wide	28744	G=0.128	A=0.871
The Genome Aggregation Database	Other	Sub	300	G=0.120	A=0.880
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.179	A=0.820
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.077	A=0.923

PMID	Title	Author	Journal
22613542	ANKRD7 and CYTL1 are novel risk genes for alcohol drinking behavior.	Chen XD	Chin Med J (Engl)

SNP ID	p-value	Traits	Study
rs4518581	4.07E-07	alcohol consumption	22613542

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr7	118614632	118614702	E081	3977
chr7	118614812	118615340	E081	4157
chr7	118639808	118640007	E081	29153
chr7	118640023	118640111	E081	29368
chr7	118646613	118646739	E081	35958
chr7	118647292	118647578	E081	36637

rs4518581