SNP Detail Info-rs4525630

Organism: Homo sapiens

Alleles: C>G / C>T

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

C==0379 (11350/29880,GnomAD)
C==0387 (11291/29118,TOPMED)
C==0414 (2075/5008,1000G)
C==0336 (1296/3854,ALSPAC)
C==0355 (1317/3708,TWINSUK)

Position: chr2:146752321 (GRCh38.p7) (2q22.3)

Phenotype: ND

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 0 Promoter around

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	C=0.388	G=0.612
1000Genomes	American	Sub	694	C=0.530	G=0.470
1000Genomes	East Asian	Sub	1008	C=0.400	G=0.600
1000Genomes	Europe	Sub	1006	C=0.392	G=0.608
1000Genomes	Global	Study-wide	5008	C=0.414	G=0.586
1000Genomes	South Asian	Sub	978	C=0.410	G=0.590
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	C=0.336	G=0.664
The Genome Aggregation Database	African	Sub	8686	C=0.388	G=0.612
The Genome Aggregation Database	American	Sub	838	C=0.510	G=0.49,
The Genome Aggregation Database	East Asian	Sub	1604	C=0.365	G=0.635
The Genome Aggregation Database	Europe	Sub	18450	C=0.368	G=0.631
The Genome Aggregation Database	Global	Study-wide	29880	C=0.379	G=0.620
The Genome Aggregation Database	Other	Sub	302	C=0.560	G=0.44,
Trans-Omics for Precision Medicine	Global	Study-wide	29118	C=0.387	G=0.612
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	C=0.355	G=0.645

PMID	Title	Author	Journal
17158188	Novel genes identified in a high-density genome wide association study for nicotine dependence.	Bierut LJ	Hum Mol Genet

SNP ID	p-value	Traits	Study
rs4525630	0.000205	nicotine dependence	17158188

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs4525630