rs4541411

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0197 (5916/29914,GnomAD)
C=0271 (7901/29118,TOPMED)
C=0214 (1072/5008,1000G)
C=0104 (401/3854,ALSPAC)
C=0107 (397/3708,TWINSUK)
chr3:164840129 (GRCh38.p7) (3q26.1)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.164840129T>C
GRCh37.p13 chr 3NC_000003.11:g.164557917T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.484C=0.516
1000GenomesAmericanSub694T=0.900C=0.100
1000GenomesEast AsianSub1008T=0.902C=0.098
1000GenomesEuropeSub1006T=0.907C=0.093
1000GenomesGlobalStudy-wide5008T=0.786C=0.214
1000GenomesSouth AsianSub978T=0.870C=0.130
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.896C=0.104
The Genome Aggregation DatabaseAfricanSub8690T=0.539C=0.461
The Genome Aggregation DatabaseAmericanSub836T=0.930C=0.070
The Genome Aggregation DatabaseEast AsianSub1614T=0.890C=0.110
The Genome Aggregation DatabaseEuropeSub18476T=0.911C=0.088
The Genome Aggregation DatabaseGlobalStudy-wide29914T=0.802C=0.197
The Genome Aggregation DatabaseOtherSub298T=0.910C=0.090
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.728C=0.271
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.893C=0.107
PMID Title Author Journal
24962325Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families.Kapoor MDrug Alcohol Depend

P-Value

SNP ID p-value Traits Study
rs45414112.07E-08alcohol dependence (age at onset)24962325

eQTL of rs4541411 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4541411 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.