rs4561856

Homo sapiens
G>A / G>C / G>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0231 (6932/29902,GnomAD)
T=0256 (1282/5008,1000G)
T=0175 (673/3854,ALSPAC)
T=0175 (648/3708,TWINSUK)
chr3:87610971 (GRCh38.p7) (3p11.2)
AD
GWASdb2
1   publication(s)
See rs on genome
1 Enhancer around
11 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.87610971G>A
GRCh38.p7 chr 3NC_000003.12:g.87610971G>C
GRCh38.p7 chr 3NC_000003.12:g.87610971G>T
GRCh37.p13 chr 3NC_000003.11:g.87660121G>A
GRCh37.p13 chr 3NC_000003.11:g.87660121G>C
GRCh37.p13 chr 3NC_000003.11:g.87660121G>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.656T=0.344
1000GenomesAmericanSub694G=0.840T=0.160
1000GenomesEast AsianSub1008G=0.636T=0.364
1000GenomesEuropeSub1006G=0.828T=0.172
1000GenomesGlobalStudy-wide5008G=0.744T=0.256
1000GenomesSouth AsianSub978G=0.820T=0.180
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.825T=0.175
The Genome Aggregation DatabaseAfricanSub8702G=0.694T=0.306
The Genome Aggregation DatabaseAmericanSub836G=0.850T=0.150
The Genome Aggregation DatabaseEast AsianSub1608G=0.655T=0.345
The Genome Aggregation DatabaseEuropeSub18454G=0.808T=0.191
The Genome Aggregation DatabaseGlobalStudy-wide29902G=0.768T=0.231
The Genome Aggregation DatabaseOtherSub302G=0.830T=0.170
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.825T=0.175
PMID Title Author Journal
22481050Genetic influences on craving for alcohol.Agrawal AAddict Behav

P-Value

SNP ID p-value Traits Study
rs45618561.79E-05alcohol craving with or without dependence22481050

eQTL of rs4561856 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4561856 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr37595546775955520E07311927

Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr37595561275956683E06712072
chr37595561275956683E06812072
chr37595561275956683E06912072
chr37595561275956683E07012072
chr37595561275956683E07112072
chr37595561275956683E07212072
chr37595561275956683E07312072
chr37595561275956683E08112072
chr37595679475956885E08113254
chr37595561275956683E08212072
chr37595679475956885E08213254