rs4585515

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
G==0223 (6695/29932,GnomAD)
G==0194 (5665/29118,TOPMED)
G==0254 (1273/5008,1000G)
G==0198 (763/3854,ALSPAC)
G==0211 (782/3708,TWINSUK)
chr5:155687216 (GRCh38.p7) (5q33.2)
AD
GWASdb2
1   publication(s)
See rs on genome
1 Enhancer around
7 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.155687216G>A
GRCh37.p13 chr 5NC_000005.9:g.155066776G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.184A=0.816
1000GenomesAmericanSub694G=0.430A=0.570
1000GenomesEast AsianSub1008G=0.274A=0.726
1000GenomesEuropeSub1006G=0.244A=0.756
1000GenomesGlobalStudy-wide5008G=0.254A=0.746
1000GenomesSouth AsianSub978G=0.220A=0.780
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.198A=0.802
The Genome Aggregation DatabaseAfricanSub8726G=0.159A=0.841
The Genome Aggregation DatabaseAmericanSub838G=0.500A=0.500
The Genome Aggregation DatabaseEast AsianSub1594G=0.283A=0.717
The Genome Aggregation DatabaseEuropeSub18472G=0.236A=0.764
The Genome Aggregation DatabaseGlobalStudy-wide29932G=0.223A=0.776
The Genome Aggregation DatabaseOtherSub302G=0.250A=0.750
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.194A=0.805
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.211A=0.789
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs45855150.00032alcohol dependence20201924

eQTL of rs4585515 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4585515 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr5155024325155024379E081-42397

Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr5155107294155109616E06740518
chr5155107294155109616E06840518
chr5155107294155109616E06940518
chr5155107294155109616E07140518
chr5155107294155109616E07240518
chr5155107294155109616E07340518
chr5155107294155109616E07440518