rs4587082

Homo sapiens
C>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0055 (1672/29960,GnomAD)
A=0071 (2080/29118,TOPMED)
A=0053 (265/5008,1000G)
A=0028 (107/3854,ALSPAC)
A=0026 (98/3708,TWINSUK)
chr5:44012370 (GRCh38.p7) (5p12)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.44012370C>A
GRCh37.p13 chr 5NC_000005.9:g.44012472C>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.852A=0.148
1000GenomesAmericanSub694C=0.980A=0.020
1000GenomesEast AsianSub1008C=1.000A=0.000
1000GenomesEuropeSub1006C=0.962A=0.038
1000GenomesGlobalStudy-wide5008C=0.947A=0.053
1000GenomesSouth AsianSub978C=0.980A=0.020
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.972A=0.028
The Genome Aggregation DatabaseAfricanSub8718C=0.869A=0.131
The Genome Aggregation DatabaseAmericanSub838C=0.990A=0.010
The Genome Aggregation DatabaseEast AsianSub1618C=1.000A=0.000
The Genome Aggregation DatabaseEuropeSub18484C=0.972A=0.027
The Genome Aggregation DatabaseGlobalStudy-wide29960C=0.944A=0.055
The Genome Aggregation DatabaseOtherSub302C=0.940A=0.060
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.928A=0.071
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.974A=0.026
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs45870820.000414alcohol dependence20201924

eQTL of rs4587082 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4587082 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.