rs4607305

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0107 (3227/29926,GnomAD)
C=0086 (2504/29118,TOPMED)
C=0081 (406/5008,1000G)
C=0090 (347/3854,ALSPAC)
C=0095 (352/3708,TWINSUK)
chr5:67714710 (GRCh38.p7) (5q13.1)
AD
GWASdb2
1   publication(s)
See rs on genome
46 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.67714710T>C
GRCh37.p13 chr 5NC_000005.9:g.67010538T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.925C=0.075
1000GenomesAmericanSub694T=0.890C=0.110
1000GenomesEast AsianSub1008T=0.924C=0.076
1000GenomesEuropeSub1006T=0.885C=0.115
1000GenomesGlobalStudy-wide5008T=0.919C=0.081
1000GenomesSouth AsianSub978T=0.960C=0.040
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.910C=0.090
The Genome Aggregation DatabaseAfricanSub8706T=0.920C=0.080
The Genome Aggregation DatabaseAmericanSub836T=0.890C=0.110
The Genome Aggregation DatabaseEast AsianSub1618T=0.933C=0.067
The Genome Aggregation DatabaseEuropeSub18464T=0.874C=0.125
The Genome Aggregation DatabaseGlobalStudy-wide29926T=0.892C=0.107
The Genome Aggregation DatabaseOtherSub302T=0.950C=0.050
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.914C=0.086
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.905C=0.095
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs46073050.0005alcohol dependence20201924

eQTL of rs4607305 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4607305 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr56701987667019938E0679338
chr56702033967020531E0679801
chr56702069867020832E06710160
chr56702685367027273E06816315
chr56701987667019938E0699338
chr56702033967020531E0699801
chr56702069867020832E06910160
chr56702147367021710E06910935
chr56702685367027273E06916315
chr56702782867028071E06917290
chr56697510466975549E070-34989
chr56697568866975935E070-34603
chr56697595566976251E070-34287
chr56697640466976579E070-33959
chr56702033967020531E0709801
chr56702069867020832E07010160
chr56697510466975549E071-34989
chr56701987667019938E0719338
chr56702033967020531E0719801
chr56702069867020832E07110160
chr56702147367021710E07110935
chr56702685367027273E07116315
chr56701987667019938E0729338
chr56702033967020531E0729801
chr56702069867020832E07210160
chr56702685367027273E07216315
chr56702033967020531E0739801
chr56702069867020832E07310160
chr56702147367021710E07310935
chr56702685367027273E07316315
chr56701987667019938E0749338
chr56702033967020531E0749801
chr56702069867020832E07410160
chr56702147367021710E07410935
chr56702685367027273E07416315
chr56697510466975549E081-34989
chr56697568866975935E081-34603
chr56699132766991408E081-19130
chr56702069867020832E08110160
chr56702147367021710E08110935
chr56702418167024233E08113643
chr56702434467024742E08113806
chr56702481767024891E08114279
chr56702782867028071E08117290
chr56702069867020832E08210160
chr56702782867028071E08217290