SNP Detail Info-rs4608580

Sequence Name	Change(s)
GRCh38.p7 chr 2	NC_000002.12:g.98244594C>T
GRCh37.p13 chr 2	NC_000002.11:g.98861057C>T

Molecule type	Change	Amino acid[Codon]	SO Term
VWA3B transcript variant 1	NM_144992.4:c.	N/A	Intron Variant
VWA3B transcript variant X1	XM_005263897.2:c.	N/A	Intron Variant
VWA3B transcript variant X7	XM_006712357.2:c.	N/A	Intron Variant
VWA3B transcript variant X13	XM_006712359.3:c.	N/A	Intron Variant
VWA3B transcript variant X15	XM_006712360.3:c.	N/A	Intron Variant
VWA3B transcript variant X4	XM_011510770.1:c.	N/A	Intron Variant
VWA3B transcript variant X5	XM_011510771.2:c.	N/A	Intron Variant
VWA3B transcript variant X6	XM_011510772.1:c.	N/A	Intron Variant
VWA3B transcript variant X8	XM_017003560.1:c.	N/A	Intron Variant
VWA3B transcript variant X9	XM_017003561.1:c.	N/A	Intron Variant
VWA3B transcript variant X10	XM_017003562.1:c.	N/A	Intron Variant
VWA3B transcript variant X11	XM_017003563.1:c.	N/A	Intron Variant
VWA3B transcript variant X11	XM_017003564.1:c.	N/A	Intron Variant
VWA3B transcript variant X12	XM_011510774.1:c.	N/A	Genic Downstream Transcript Variant
VWA3B transcript variant X14	XM_011510775.2:c.	N/A	Genic Downstream Transcript Variant
VWA3B transcript variant X16	XR_244881.1:n.	N/A	Intron Variant
VWA3B transcript variant X2	XR_922884.1:n.	N/A	Intron Variant
VWA3B transcript variant X3	XR_922885.2:n.	N/A	Intron Variant
VWA3B transcript variant X15	XR_922887.1:n.	N/A	Genic Downstream Transcript Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	C=0.365	T=0.635
1000Genomes	American	Sub	694	C=0.500	T=0.500
1000Genomes	East Asian	Sub	1008	C=0.202	T=0.798
1000Genomes	Europe	Sub	1006	C=0.456	T=0.544
1000Genomes	Global	Study-wide	5008	C=0.330	T=0.670
1000Genomes	South Asian	Sub	978	C=0.160	T=0.840
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	C=0.470	T=0.530
The Genome Aggregation Database	African	Sub	8678	C=0.375	T=0.625
The Genome Aggregation Database	American	Sub	830	C=0.520	T=0.480
The Genome Aggregation Database	East Asian	Sub	1614	C=0.205	T=0.795
The Genome Aggregation Database	Europe	Sub	18452	C=0.476	T=0.523
The Genome Aggregation Database	Global	Study-wide	29876	C=0.432	T=0.568
The Genome Aggregation Database	Other	Sub	302	C=0.330	T=0.670
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	C=0.456	T=0.544

PMID	Title	Author	Journal
19268276	Genome-wide association study of smoking initiation and current smoking.	Vink JM	Am J Hum Genet

SNP ID	p-value	Traits	Study
rs4608580	7.91E-05	nicotine smoking	19268276

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr2	98869934	98870260	E067	8877
chr2	98857396	98857796	E068	-3261
chr2	98857396	98857796	E069	-3261
chr2	98828656	98828708	E070	-32349
chr2	98857396	98857796	E070	-3261
chr2	98868910	98869148	E070	7853
chr2	98869934	98870260	E070	8877
chr2	98893710	98894215	E070	32653
chr2	98857396	98857796	E071	-3261
chr2	98850742	98850851	E072	-10206
chr2	98851381	98851518	E072	-9539
chr2	98857396	98857796	E072	-3261
chr2	98850742	98850851	E074	-10206
chr2	98828461	98828545	E081	-32512
chr2	98828656	98828708	E081	-32349
chr2	98868910	98869148	E081	7853
chr2	98869934	98870260	E081	8877
chr2	98828656	98828708	E082	-32349
chr2	98868910	98869148	E082	7853
chr2	98869934	98870260	E082	8877

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr2	98858540	98858821	E067	-2236
chr2	98858540	98858821	E068	-2236
chr2	98858540	98858821	E069	-2236
chr2	98858540	98858821	E071	-2236
chr2	98858540	98858821	E072	-2236
chr2	98858540	98858821	E074	-2236

rs4608580