SNP Detail Info-rs4610908

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0242 (5012/20715,GnomAD)
A=0198 (749/3775,1000G)
A=0245 (908/3708,TWINSUK)
A=0244 (704/2889,ALSPAC)

Position: chrX:35166418 (GRCh38.p7) (Xp21.1)

Phenotype: AD | ND

Dataset:

GWASdb2

Publications: 4 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr X	NC_000023.11:g.35166418G>A
GRCh37.p13 chr X	NC_000023.10:g.35184535G>A

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1003	G=0.713	A=0.287
1000Genomes	American	Sub	524	G=0.850	A=0.150
1000Genomes	East Asian	Sub	764	G=0.940	A=0.060
1000Genomes	Europe	Sub	766	G=0.760	A=0.240
1000Genomes	Global	Study-wide	3775	G=0.802	A=0.198
1000Genomes	South Asian	Sub	718	G=0.790	A=0.210
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	2889	G=0.756	A=0.244
The Genome Aggregation Database	African	Sub	5832	G=0.725	A=0.275
The Genome Aggregation Database	American	Sub	613	G=0.890	A=0.110
The Genome Aggregation Database	East Asian	Sub	1017	G=0.936	A=0.064
The Genome Aggregation Database	Europe	Sub	13069	G=0.753	A=0.246
The Genome Aggregation Database	Global	Study-wide	20715	G=0.758	A=0.242
The Genome Aggregation Database	Other	Sub	184	G=0.710	A=0.290
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.755	A=0.245

PMID	Title	Author	Journal
22096494	A novel, functional and replicable risk gene region for alcohol dependence identified by genome-wide association study.	Zuo L	PLoS One
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res
20202923	A genome-wide association study of alcohol dependence.	Bierut LJ	Proc Natl Acad Sci U S A
22488850	Genome-wide search for replicable risk gene regions in alcohol and nicotine co-dependence.	Zuo L	Am J Med Genet B Neuropsychiatr Genet

SNP ID	p-value	Traits	Study
rs4610908	0.00000032	alcohol and nictotine co-dependence	22488850
rs4610908	0.00000057	alcohol dependence	22096494
rs4610908	0.00000549	alcohol dependence	20202923
rs4610908	0.000581	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs4610908