rs4611850

Homo sapiens
T>A / T>G
None
Check p-value
SNV (Single Nucleotide Variation)
T==0497 (14887/29924,GnomAD)
G=0453 (13213/29118,TOPMED)
T==0427 (2140/5008,1000G)
T==0467 (1798/3854,ALSPAC)
T==0468 (1735/3708,TWINSUK)
chr3:17757157 (GRCh38.p7) (3p24.3)
AD
GWASdb2
1   publication(s)
See rs on genome
3 Enhancers around
18 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.17757157T>A
GRCh38.p7 chr 3NC_000003.12:g.17757157T>G
GRCh37.p13 chr 3NC_000003.11:g.17798649T>A
GRCh37.p13 chr 3NC_000003.11:g.17798649T>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.732G=0.268
1000GenomesAmericanSub694T=0.370G=0.630
1000GenomesEast AsianSub1008T=0.066G=0.934
1000GenomesEuropeSub1006T=0.474G=0.526
1000GenomesGlobalStudy-wide5008T=0.427G=0.573
1000GenomesSouth AsianSub978T=0.380G=0.620
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.467G=0.533
The Genome Aggregation DatabaseAfricanSub8720T=0.678G=0.322
The Genome Aggregation DatabaseAmericanSub836T=0.280G=0.720
The Genome Aggregation DatabaseEast AsianSub1620T=0.041G=0.959
The Genome Aggregation DatabaseEuropeSub18446T=0.463G=0.536
The Genome Aggregation DatabaseGlobalStudy-wide29924T=0.497G=0.502
The Genome Aggregation DatabaseOtherSub302T=0.420G=0.580
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.546G=0.453
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.468G=0.532
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs46118500.00065alcohol dependence20201924

eQTL of rs4611850 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4611850 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr3110788447110788519E06840377
chr3110793901110794007E07145831
chr3110788447110788519E07240377



Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr3110788741110791878E06740671
chr3110791902110793096E06743832
chr3110788741110791878E06840671
chr3110788741110791878E06940671
chr3110791902110793096E06943832
chr3110788741110791878E07040671
chr3110791902110793096E07043832
chr3110788741110791878E07140671
chr3110788741110791878E07240671
chr3110791902110793096E07243832
chr3110788741110791878E07340671
chr3110791902110793096E07343832
chr3110788741110791878E07440671
chr3110788741110791878E08140671
chr3110791902110793096E08143832
chr3110788741110791878E08240671
chr3110791902110793096E08243832
chr3110793520110793703E08245450