rs4629506

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
T==0313 (9353/29820,GnomAD)
T==0353 (10303/29118,TOPMED)
T==0304 (1524/5008,1000G)
T==0220 (848/3854,ALSPAC)
T==0227 (843/3708,TWINSUK)
chr4:65718188 (GRCh38.p7) (4q13.2)
ND
GWASdb2
1   publication(s)
See rs on genome
5 Enhancers around
28 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.65718188T>C
GRCh37.p13 chr 4NC_000004.11:g.66583906T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.610C=0.390
1000GenomesAmericanSub694T=0.230C=0.770
1000GenomesEast AsianSub1008T=0.106C=0.894
1000GenomesEuropeSub1006T=0.251C=0.749
1000GenomesGlobalStudy-wide5008T=0.304C=0.696
1000GenomesSouth AsianSub978T=0.200C=0.800
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.220C=0.780
The Genome Aggregation DatabaseAfricanSub8696T=0.565C=0.435
The Genome Aggregation DatabaseAmericanSub836T=0.220C=0.780
The Genome Aggregation DatabaseEast AsianSub1568T=0.085C=0.915
The Genome Aggregation DatabaseEuropeSub18418T=0.219C=0.780
The Genome Aggregation DatabaseGlobalStudy-wide29820T=0.313C=0.686
The Genome Aggregation DatabaseOtherSub302T=0.290C=0.710
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.353C=0.646
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.227C=0.773
PMID Title Author Journal
20158304A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.Lind PATwin Res Hum Genet

P-Value

SNP ID p-value Traits Study
rs46295064.28E-05alcohol and nictotine co-dependence20158304

eQTL of rs4629506 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4629506 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr46654047266540531E070-43375
chr46654123166541311E070-42595
chr46654123166541311E082-42595
chr46655494066555130E082-28776
chr46656137466561436E082-22470


Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr46653460066534660E067-49246
chr46653471566535359E067-48547
chr46653543766536793E067-47113
chr46653460066534660E068-49246
chr46653543766536793E068-47113
chr46653460066534660E069-49246
chr46653471566535359E069-48547
chr46653543766536793E069-47113
chr46653460066534660E070-49246
chr46653471566535359E070-48547
chr46653543766536793E070-47113
chr46653726066537351E070-46555
chr46653543766536793E071-47113
chr46653460066534660E072-49246
chr46653543766536793E072-47113
chr46653726066537351E072-46555
chr46653543766536793E073-47113
chr46653460066534660E074-49246
chr46653471566535359E074-48547
chr46653543766536793E074-47113
chr46653460066534660E081-49246
chr46653471566535359E081-48547
chr46653543766536793E081-47113
chr46653726066537351E081-46555
chr46653460066534660E082-49246
chr46653471566535359E082-48547
chr46653543766536793E082-47113
chr46653726066537351E082-46555