rs4641724

Homo sapiens
C>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0133 (3992/29944,GnomAD)
A=0149 (4338/29118,TOPMED)
A=0122 (609/5008,1000G)
A=0074 (284/3854,ALSPAC)
A=0081 (299/3708,TWINSUK)
chr15:98541531 (GRCh38.p7) (15q26.3)
AD
GWASdb2
1   publication(s)
See rs on genome
7 Enhancers around
8 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 15NC_000015.10:g.98541531C>A
GRCh37.p13 chr 15NC_000015.9:g.99084760C>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.725A=0.275
1000GenomesAmericanSub694C=0.900A=0.100
1000GenomesEast AsianSub1008C=0.986A=0.014
1000GenomesEuropeSub1006C=0.918A=0.082
1000GenomesGlobalStudy-wide5008C=0.878A=0.122
1000GenomesSouth AsianSub978C=0.920A=0.080
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.926A=0.074
The Genome Aggregation DatabaseAfricanSub8706C=0.765A=0.235
The Genome Aggregation DatabaseAmericanSub836C=0.920A=0.080
The Genome Aggregation DatabaseEast AsianSub1614C=0.884A=0.116
The Genome Aggregation DatabaseEuropeSub18488C=0.910A=0.089
The Genome Aggregation DatabaseGlobalStudy-wide29944C=0.866A=0.133
The Genome Aggregation DatabaseOtherSub300C=0.890A=0.110
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.851A=0.149
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.919A=0.081
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs46417240.000733alcohol dependence20201924

eQTL of rs4641724 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4641724 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr159906216199062832E067-21928
chr159906216199062832E068-21928
chr159907546099075556E068-9204
chr159904983099050111E069-34649
chr159912373099123834E07338970
chr159912387899124193E07339118
chr159909259199092732E0817831





Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr159909010299092453E0675342
chr159909010299092453E0685342
chr159909010299092453E0695342
chr159909010299092453E0715342
chr159909010299092453E0725342
chr159909010299092453E0735342
chr159909010299092453E0745342
chr159909010299092453E0825342