rs4662907

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0397 (11870/29882,GnomAD)
A=0349 (10174/29118,TOPMED)
A=0422 (2111/5008,1000G)
A=0456 (1758/3854,ALSPAC)
A=0469 (1740/3708,TWINSUK)
chr2:129232624 (GRCh38.p7) (2q21.1)
AD
GWASdb2
1   publication(s)
See rs on genome
16 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.129232624G>A
GRCh37.p13 chr 2NC_000002.11:g.129990197G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.835A=0.165
1000GenomesAmericanSub694G=0.490A=0.510
1000GenomesEast AsianSub1008G=0.293A=0.707
1000GenomesEuropeSub1006G=0.572A=0.428
1000GenomesGlobalStudy-wide5008G=0.578A=0.422
1000GenomesSouth AsianSub978G=0.600A=0.400
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.544A=0.456
The Genome Aggregation DatabaseAfricanSub8694G=0.790A=0.210
The Genome Aggregation DatabaseAmericanSub838G=0.470A=0.530
The Genome Aggregation DatabaseEast AsianSub1614G=0.222A=0.778
The Genome Aggregation DatabaseEuropeSub18436G=0.553A=0.446
The Genome Aggregation DatabaseGlobalStudy-wide29882G=0.602A=0.397
The Genome Aggregation DatabaseOtherSub300G=0.610A=0.390
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.650A=0.349
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.531A=0.469
PMID Title Author Journal
24962325Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families.Kapoor MDrug Alcohol Depend

P-Value

SNP ID p-value Traits Study
rs46629075.69E-06alcohol dependence (age at onset)24962325

eQTL of rs4662907 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4662907 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr2129990903129991022E070706
chr2129991443129991904E0701246
chr2129990903129991022E081706
chr2129991443129991904E0811246
chr2129996773129997036E0816576
chr2130010223130010353E08120026
chr2130010398130011293E08120201
chr2130038915130039052E08148718
chr2130039472130039687E08149275
chr2130039843130039996E08149646
chr2129996773129997036E0826576
chr2130010223130010353E08220026
chr2130038591130038845E08248394
chr2130038915130039052E08248718
chr2130039472130039687E08249275
chr2130039843130039996E08249646