rs470790

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
T==0446 (13378/29942,GnomAD)
T==0433 (12625/29118,TOPMED)
T==0402 (2012/5008,1000G)
C=0457 (1760/3854,ALSPAC)
C=0456 (1691/3708,TWINSUK)
chr6:10460327 (GRCh38.p7) (6p24.3)
AD
GWASdb2
1   publication(s)
See rs on genome
2 Enhancers around
3 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.10460327T>C
GRCh37.p13 chr 6NC_000006.11:g.10460560T>C
MRPL48P1 pseudogeneNG_002430.2:g.363A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.242C=0.758
1000GenomesAmericanSub694T=0.480C=0.520
1000GenomesEast AsianSub1008T=0.506C=0.494
1000GenomesEuropeSub1006T=0.526C=0.474
1000GenomesGlobalStudy-wide5008T=0.402C=0.598
1000GenomesSouth AsianSub978T=0.330C=0.670
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.543C=0.457
The Genome Aggregation DatabaseAfricanSub8722T=0.296C=0.704
The Genome Aggregation DatabaseAmericanSub836T=0.440C=0.560
The Genome Aggregation DatabaseEast AsianSub1604T=0.484C=0.516
The Genome Aggregation DatabaseEuropeSub18478T=0.514C=0.485
The Genome Aggregation DatabaseGlobalStudy-wide29942T=0.446C=0.553
The Genome Aggregation DatabaseOtherSub302T=0.480C=0.520
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.433C=0.566
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.544C=0.456
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs4707900.000775alcohol dependence20201924

eQTL of rs470790 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs470790 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr61044834110448736E070-11824
chr61043427110435583E071-24977


Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr61042548010428027E067-32533
chr61042548010428027E068-32533
chr61042548010428027E073-32533