rs4730908

Homo sapiens
C>G
None
Check p-value
SNV (Single Nucleotide Variation)
C==0428 (12789/29858,GnomAD)
C==0484 (14092/29118,TOPMED)
C==0396 (1981/5008,1000G)
C==0372 (1434/3854,ALSPAC)
C==0360 (1334/3708,TWINSUK)
chr7:119017956 (GRCh38.p7) (7q31.31)
AD
GWASdb2
1   publication(s)
See rs on genome
6 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.119017956C>G
GRCh37.p13 chr 7NC_000007.13:g.118658010C>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.691G=0.309
1000GenomesAmericanSub694C=0.300G=0.700
1000GenomesEast AsianSub1008C=0.329G=0.671
1000GenomesEuropeSub1006C=0.350G=0.650
1000GenomesGlobalStudy-wide5008C=0.396G=0.604
1000GenomesSouth AsianSub978C=0.180G=0.820
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.372G=0.628
The Genome Aggregation DatabaseAfricanSub8708C=0.630G=0.370
The Genome Aggregation DatabaseAmericanSub834C=0.290G=0.710
The Genome Aggregation DatabaseEast AsianSub1580C=0.318G=0.682
The Genome Aggregation DatabaseEuropeSub18434C=0.350G=0.650
The Genome Aggregation DatabaseGlobalStudy-wide29858C=0.428G=0.571
The Genome Aggregation DatabaseOtherSub302C=0.350G=0.650
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.484G=0.516
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.360G=0.640
PMID Title Author Journal
22613542ANKRD7 and CYTL1 are novel risk genes for alcohol drinking behavior.Chen XDChin Med J (Engl)

P-Value

SNP ID p-value Traits Study
rs47309081.12E-07alcohol consumption22613542

eQTL of rs4730908 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4730908 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr7118614632118614702E081-43308
chr7118614812118615340E081-42670
chr7118639808118640007E081-18003
chr7118640023118640111E081-17899
chr7118646613118646739E081-11271
chr7118647292118647578E081-10432