rs4735183

Homo sapiens
G>T
None
Check p-value
SNV (Single Nucleotide Variation)
G==0331 (9900/29908,GnomAD)
G==0355 (10349/29118,TOPMED)
G==0257 (1286/5008,1000G)
G==0292 (1127/3854,ALSPAC)
G==0293 (1088/3708,TWINSUK)
chr8:92556715 (GRCh38.p7) (8q22.1)
AD
GWASdb2
1   publication(s)
See rs on genome
66 Enhancers around
6 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.92556715G>T
GRCh37.p13 chr 8NC_000008.10:g.93568943G>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.464T=0.536
1000GenomesAmericanSub694G=0.320T=0.680
1000GenomesEast AsianSub1008G=0.012T=0.988
1000GenomesEuropeSub1006G=0.325T=0.675
1000GenomesGlobalStudy-wide5008G=0.257T=0.743
1000GenomesSouth AsianSub978G=0.110T=0.890
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.292T=0.708
The Genome Aggregation DatabaseAfricanSub8698G=0.456T=0.544
The Genome Aggregation DatabaseAmericanSub828G=0.320T=0.680
The Genome Aggregation DatabaseEast AsianSub1610G=0.017T=0.983
The Genome Aggregation DatabaseEuropeSub18470G=0.300T=0.699
The Genome Aggregation DatabaseGlobalStudy-wide29908G=0.331T=0.669
The Genome Aggregation DatabaseOtherSub302G=0.290T=0.710
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.355T=0.644
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.293T=0.707
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs47351830.00094alcohol dependence20201924

eQTL of rs4735183 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4735183 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr89352566693525886E067-43057
chr89352595093526019E067-42924
chr89352941093529516E067-39427
chr89352996093530041E067-38902
chr89353015093530339E067-38604
chr89355064393550826E069-18117
chr89355201893552913E069-16030
chr89352638393526556E070-42387
chr89352855093528856E070-40087
chr89353100993531059E070-37884
chr89353107293531112E070-37831
chr89357665293576789E0707709
chr89361518493615262E07046241
chr89361532393615475E07046380
chr89361790393618683E07048960
chr89361870593618820E07049762
chr89353777293537856E071-31087
chr89355064393550826E071-18117
chr89355170593551827E071-17116
chr89355187493551971E071-16972
chr89355201893552913E071-16030
chr89356801393568097E071-846
chr89356812193568355E071-588
chr89359973193600188E07130788
chr89360019793600352E07131254
chr89355064393550826E072-18117
chr89355170593551827E072-17116
chr89355187493551971E072-16972
chr89355201893552913E072-16030
chr89359973193600188E07230788
chr89360019793600352E07231254
chr89355201893552913E074-16030
chr89359952093599664E07430577
chr89359973193600188E07430788
chr89360019793600352E07431254
chr89352083293520973E081-47970
chr89352103493521084E081-47859
chr89352112893521195E081-47748
chr89352126293522368E081-46575
chr89352507593525125E081-43818
chr89352526893525469E081-43474
chr89352566693525886E081-43057
chr89352595093526019E081-42924
chr89352619593526263E081-42680
chr89352638393526556E081-42387
chr89352855093528856E081-40087
chr89357665293576789E0817709
chr89357693393576983E0817990
chr89361715693617442E08148213
chr89361763793617723E08148694
chr89361773293617863E08148789
chr89361790393618683E08148960
chr89361870593618820E08149762
chr89352566693525886E082-43057
chr89352595093526019E082-42924
chr89352619593526263E082-42680
chr89352638393526556E082-42387
chr89352855093528856E082-40087
chr89353143093531665E082-37278
chr89353180093531850E082-37093
chr89353187493531959E082-36984
chr89353200193532073E082-36870
chr89353239593532785E082-36158
chr89353309293533287E082-35656
chr89361790393618683E08248960
chr89361870593618820E08249762








Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr89352658493528492E067-40451
chr89352658493528492E071-40451
chr89352658493528492E072-40451
chr89352658493528492E073-40451
chr89352658493528492E074-40451
chr89352658493528492E082-40451