rs4749705

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0227 (6823/29946,GnomAD)
T=0207 (6042/29118,TOPMED)
T=0254 (1272/5008,1000G)
T=0227 (873/3854,ALSPAC)
T=0233 (865/3708,TWINSUK)
chr10:32131163 (GRCh38.p7) (10p11.22)
AD
GWASdb2
1   publication(s)
See rs on genome
18 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.32131163C>T
GRCh37.p13 chr 10NC_000010.10:g.32420091C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.851T=0.149
1000GenomesAmericanSub694C=0.770T=0.230
1000GenomesEast AsianSub1008C=0.575T=0.425
1000GenomesEuropeSub1006C=0.785T=0.215
1000GenomesGlobalStudy-wide5008C=0.746T=0.254
1000GenomesSouth AsianSub978C=0.720T=0.280
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.773T=0.227
The Genome Aggregation DatabaseAfricanSub8714C=0.839T=0.161
The Genome Aggregation DatabaseAmericanSub836C=0.760T=0.240
The Genome Aggregation DatabaseEast AsianSub1614C=0.569T=0.431
The Genome Aggregation DatabaseEuropeSub18484C=0.758T=0.241
The Genome Aggregation DatabaseGlobalStudy-wide29946C=0.772T=0.227
The Genome Aggregation DatabaseOtherSub298C=0.770T=0.230
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.792T=0.207
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.767T=0.233
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs47497050.00092alcohol dependence20201924

eQTL of rs4749705 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4749705 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr103245889432458944E06738803
chr103241203932412089E068-8002
chr103241221032412648E068-7443
chr103241411532414254E069-5837
chr103241427032414356E069-5735
chr103242786132428899E0697770
chr103245850832458859E06938417
chr103245889432458944E06938803
chr103245911732459188E06939026
chr103241203932412089E071-8002
chr103241358232413632E071-6459
chr103241411532414254E071-5837
chr103241427032414356E071-5735
chr103242769432427791E0717603
chr103245101732451105E08130926
chr103245112632451176E08131035
chr103245889432458944E08138803
chr103245984932459939E08139758