rs4756348

Homo sapiens
T>G
LOC107984326 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T==0347 (10391/29886,GnomAD)
T==0332 (9677/29118,TOPMED)
T==0455 (2280/5008,1000G)
T==0392 (1512/3854,ALSPAC)
T==0391 (1451/3708,TWINSUK)
chr11:36755789 (GRCh38.p7) (11p12)
AD
GWASdb2
1   publication(s)
See rs on genome
2 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.36755789T>G
GRCh37.p13 chr 11NC_000011.9:g.36777339T>G

Gene: LOC107984326, uncharacterized LOC107984326(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC107984326 transcript variant X1XR_001748187.1:n.N/AIntron Variant
LOC107984326 transcript variant X2XR_001748188.1:n.N/AGenic Downstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.168G=0.832
1000GenomesAmericanSub694T=0.470G=0.530
1000GenomesEast AsianSub1008T=0.740G=0.260
1000GenomesEuropeSub1006T=0.414G=0.586
1000GenomesGlobalStudy-wide5008T=0.455G=0.545
1000GenomesSouth AsianSub978T=0.580G=0.420
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.392G=0.608
The Genome Aggregation DatabaseAfricanSub8706T=0.212G=0.788
The Genome Aggregation DatabaseAmericanSub834T=0.480G=0.520
The Genome Aggregation DatabaseEast AsianSub1608T=0.747G=0.253
The Genome Aggregation DatabaseEuropeSub18436T=0.370G=0.629
The Genome Aggregation DatabaseGlobalStudy-wide29886T=0.347G=0.652
The Genome Aggregation DatabaseOtherSub302T=0.390G=0.610
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.332G=0.667
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.391G=0.609
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs47563480.000493alcohol dependence21314694

eQTL of rs4756348 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4756348 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr113680785836807908E07030519
chr113676595536766650E071-10689