rs4759802

Homo sapiens
A>G / A>T
None
Check p-value
SNV (Single Nucleotide Variation)
A==0183 (5481/29940,GnomAD)
A==0223 (6516/29118,TOPMED)
A==0169 (848/5008,1000G)
A==0137 (527/3854,ALSPAC)
A==0128 (475/3708,TWINSUK)
chr12:130922632 (GRCh38.p7) (12q24.33)
ND
GWASdb2
1   publication(s)
See rs on genome
10 Enhancers around
1 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 12NC_000012.12:g.130922632A>G
GRCh38.p7 chr 12NC_000012.12:g.130922632A>T
GRCh37.p13 chr 12NC_000012.11:g.131407177A>G
GRCh37.p13 chr 12NC_000012.11:g.131407177A>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.358G=0.642
1000GenomesAmericanSub694A=0.110G=0.890
1000GenomesEast AsianSub1008A=0.106G=0.894
1000GenomesEuropeSub1006A=0.147G=0.853
1000GenomesGlobalStudy-wide5008A=0.169G=0.831
1000GenomesSouth AsianSub978A=0.050G=0.950
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.137G=0.863
The Genome Aggregation DatabaseAfricanSub8706A=0.325G=0.675
The Genome Aggregation DatabaseAmericanSub836A=0.090G=0.91,
The Genome Aggregation DatabaseEast AsianSub1620A=0.091G=0.909
The Genome Aggregation DatabaseEuropeSub18476A=0.128G=0.871
The Genome Aggregation DatabaseGlobalStudy-wide29940A=0.183G=0.816
The Genome Aggregation DatabaseOtherSub302A=0.190G=0.81,
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.223G=0.776
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.128G=0.872
PMID Title Author Journal
19268276Genome-wide association study of smoking initiation and current smoking.Vink JMAm J Hum Genet

P-Value

SNP ID p-value Traits Study
rs47598027.44E-05nicotine smoking19268276

eQTL of rs4759802 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4759802 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr129577893195779024E068-24832
chr129577851995778599E069-25257
chr129577865695778706E069-25150
chr129584086895840967E07037012
chr129584086895840967E07137012
chr129577764495778292E073-25564
chr129577851995778599E073-25257
chr129577865695778706E073-25150
chr129584086895840967E08137012
chr129584086895840967E08237012







Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr129583995695840867E08236100