rs4770403

Homo sapiens
G>A
SGCG : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A=0142 (4270/29958,GnomAD)
A=0154 (4503/29116,TOPMED)
A=0125 (627/5008,1000G)
A=0188 (726/3854,ALSPAC)
A=0196 (726/3708,TWINSUK)
chr13:23180988 (GRCh38.p7) (13q12.12)
AD
GWASdb2 | GWASCatalog
2   publication(s)
See rs on genome
9 Enhancers around
3 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 13NC_000013.11:g.23180988G>A
GRCh37.p13 chr 13NC_000013.10:g.23755127G>A
SGCG RefSeqGene LRG_207

Gene: SGCG, sarcoglycan gamma(plus strand)

Molecule type Change Amino acid[Codon] SO Term
SGCG transcriptNM_000231.2:c.N/A5 Prime UTR Variant
SGCG transcript variant X1XM_006719861.3:c.N/AIntron Variant
SGCG transcript variant X2XM_005266505.2:c.N/A5 Prime UTR Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.907A=0.093
1000GenomesAmericanSub694G=0.890A=0.110
1000GenomesEast AsianSub1008G=0.852A=0.148
1000GenomesEuropeSub1006G=0.816A=0.184
1000GenomesGlobalStudy-wide5008G=0.875A=0.125
1000GenomesSouth AsianSub978G=0.910A=0.090
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.812A=0.188
The Genome Aggregation DatabaseAfricanSub8716G=0.904A=0.096
The Genome Aggregation DatabaseAmericanSub838G=0.890A=0.110
The Genome Aggregation DatabaseEast AsianSub1618G=0.854A=0.146
The Genome Aggregation DatabaseEuropeSub18484G=0.836A=0.163
The Genome Aggregation DatabaseGlobalStudy-wide29958G=0.857A=0.142
The Genome Aggregation DatabaseOtherSub302G=0.730A=0.270
Trans-Omics for Precision MedicineGlobalStudy-wide29116G=0.845A=0.154
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.804A=0.196
PMID Title Author Journal
22004471Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster.Frank JAddict Biol
22170014Fine mapping of a QTL on chromosome 13 for submaximal exercise capacity training response: the HERITAGE Family Study.Rice TKEur J Appl Physiol

P-Value

SNP ID p-value Traits Study
rs47704036E-06alcohol dependence22004471

eQTL of rs4770403 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4770403 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr132377665923776791E06721532
chr132370828923708477E070-46650
chr132370849223708650E070-46477
chr132380363523804025E07048508
chr132380479023804856E07049663
chr132380492423805062E07049797
chr132372078823720872E081-34255
chr132372087923721620E081-33507
chr132372198623722276E081-32851



Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr132373322823735701E072-19426
chr132373574923735914E081-19213
chr132373322823735701E082-19426