rs4784281

Homo sapiens
A>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0059 (1789/29972,GnomAD)
T=0076 (2235/29118,TOPMED)
T=0061 (305/5008,1000G)
T=0035 (134/3854,ALSPAC)
T=0027 (101/3708,TWINSUK)
chr16:52970596 (GRCh38.p7) (16q12.2)
AD
GWASdb2
1   publication(s)
See rs on genome
12 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 16NC_000016.10:g.52970596A>T
GRCh37.p13 chr 16NC_000016.9:g.53004508A>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.868T=0.132
1000GenomesAmericanSub694A=0.890T=0.110
1000GenomesEast AsianSub1008A=0.996T=0.004
1000GenomesEuropeSub1006A=0.966T=0.034
1000GenomesGlobalStudy-wide5008A=0.939T=0.061
1000GenomesSouth AsianSub978A=0.980T=0.020
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.965T=0.035
The Genome Aggregation DatabaseAfricanSub8714A=0.863T=0.137
The Genome Aggregation DatabaseAmericanSub838A=0.910T=0.090
The Genome Aggregation DatabaseEast AsianSub1620A=0.993T=0.007
The Genome Aggregation DatabaseEuropeSub18498A=0.973T=0.026
The Genome Aggregation DatabaseGlobalStudy-wide29972A=0.940T=0.059
The Genome Aggregation DatabaseOtherSub302A=0.970T=0.030
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.923T=0.076
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.973T=0.027
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs47842810.000873alcohol dependence21314694

eQTL of rs4784281 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4784281 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr165299802952998079E070-6429
chr165299834652998466E070-6042
chr165300144953001533E070-2975
chr165300161453001697E070-2811
chr165300175353001850E070-2658
chr165300233953002435E070-2073
chr165302223953022324E07017731
chr165302252153022575E07018013
chr165303590953036064E07031401
chr165303614353036383E07031635
chr165302702653027133E08122518
chr165302719253027355E08122684