rs4802205

Homo sapiens
G>A
ZNF224 : 2KB Upstream Variant
Check p-value
SNV (Single Nucleotide Variation)
G==0295 (8770/29702,GnomAD)
G==0333 (9723/29118,TOPMED)
G==0396 (1983/5008,1000G)
G==0158 (609/3854,ALSPAC)
G==0160 (595/3708,TWINSUK)
chr19:44093276 (GRCh38.p7) (19q13.31)
AD
GWASdb2
1   publication(s)
See rs on genome
13 Enhancers around
91 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 19NC_000019.10:g.44093276G>A
GRCh37.p13 chr 19NC_000019.9:g.44597429G>A

Gene: ZNF224, zinc finger protein 224(plus strand): 2KB Upstream Variant

Molecule type Change Amino acid[Codon] SO Term
ZNF224 transcriptNM_001321645.1:c.N/AUpstream Transcript Variant
ZNF224 transcriptNM_013398.3:c.N/AUpstream Transcript Variant
ZNF224 transcript variant X1XM_017027261.1:c.N/AN/A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.518A=0.482
1000GenomesAmericanSub694G=0.460A=0.540
1000GenomesEast AsianSub1008G=0.473A=0.527
1000GenomesEuropeSub1006G=0.193A=0.807
1000GenomesGlobalStudy-wide5008G=0.396A=0.604
1000GenomesSouth AsianSub978G=0.310A=0.690
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.158A=0.842
The Genome Aggregation DatabaseAfricanSub8640G=0.461A=0.539
The Genome Aggregation DatabaseAmericanSub834G=0.490A=0.510
The Genome Aggregation DatabaseEast AsianSub1610G=0.453A=0.547
The Genome Aggregation DatabaseEuropeSub18316G=0.195A=0.804
The Genome Aggregation DatabaseGlobalStudy-wide29702G=0.295A=0.704
The Genome Aggregation DatabaseOtherSub302G=0.230A=0.770
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.333A=0.666
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.160A=0.840
PMID Title Author Journal
23743675A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.Kapoor MHum Genet

P-Value

SNP ID p-value Traits Study
rs48022057.98E-05alcohol consumption23743675

eQTL of rs4802205 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
Chr19:44597429ZNF284ENSG00000186026.6G>A8.0274e-421132Cerebellar_Hemisphere

meQTL of rs4802205 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr194455748644557536E067-39893
chr194455748644557536E068-39893
chr194461888344619034E06821454
chr194460014844600194E0692719
chr194455793344557994E070-39435
chr194460014844600194E0702719
chr194461888344619034E07021454
chr194461903744619091E07021608
chr194461912544619165E07021696
chr194461888344619034E07121454
chr194455748644557536E081-39893
chr194455748644557536E082-39893
chr194460081644600930E0823387







Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr194455479344554904E067-42525
chr194455494844556685E067-40744
chr194455673144556943E067-40486
chr194457541944575610E067-21819
chr194457564244577153E067-20276
chr194459804744599722E067618
chr194461592544616789E06718496
chr194461680644618482E06719377
chr194464488144646741E06747452
chr194455494844556685E068-40744
chr194455673144556943E068-40486
chr194457541944575610E068-21819
chr194457564244577153E068-20276
chr194459781244597885E068383
chr194459793544597989E068506
chr194459804744599722E068618
chr194461578744615827E06818358
chr194461592544616789E06818496
chr194461680644618482E06819377
chr194464474344644803E06847314
chr194464488144646741E06847452
chr194455494844556685E069-40744
chr194455673144556943E069-40486
chr194457541944575610E069-21819
chr194457564244577153E069-20276
chr194459804744599722E069618
chr194461578744615827E06918358
chr194461592544616789E06918496
chr194461680644618482E06919377
chr194464488144646741E06947452
chr194455494844556685E070-40744
chr194455673144556943E070-40486
chr194457541944575610E070-21819
chr194457564244577153E070-20276
chr194459804744599722E070618
chr194461592544616789E07018496
chr194461680644618482E07019377
chr194464474344644803E07047314
chr194464488144646741E07047452
chr194455494844556685E071-40744
chr194455673144556943E071-40486
chr194457541944575610E071-21819
chr194457564244577153E071-20276
chr194459804744599722E071618
chr194461578744615827E07118358
chr194461592544616789E07118496
chr194461680644618482E07119377
chr194464474344644803E07147314
chr194464488144646741E07147452
chr194455494844556685E072-40744
chr194455673144556943E072-40486
chr194457541944575610E072-21819
chr194457564244577153E072-20276
chr194459804744599722E072618
chr194461592544616789E07218496
chr194461680644618482E07219377
chr194464474344644803E07247314
chr194464488144646741E07247452
chr194455494844556685E073-40744
chr194455673144556943E073-40486
chr194457541944575610E073-21819
chr194457564244577153E073-20276
chr194459804744599722E073618
chr194461592544616789E07318496
chr194461680644618482E07319377
chr194464488144646741E07347452
chr194455494844556685E074-40744
chr194455673144556943E074-40486
chr194457541944575610E074-21819
chr194457564244577153E074-20276
chr194459804744599722E074618
chr194461592544616789E07418496
chr194461680644618482E07419377
chr194464488144646741E07447452
chr194455494844556685E081-40744
chr194455673144556943E081-40486
chr194457541944575610E081-21819
chr194457564244577153E081-20276
chr194459804744599722E081618
chr194461592544616789E08118496
chr194461680644618482E08119377
chr194464488144646741E08147452
chr194455494844556685E082-40744
chr194455673144556943E082-40486
chr194457541944575610E082-21819
chr194457564244577153E082-20276
chr194459804744599722E082618
chr194461592544616789E08218496
chr194461680644618482E08219377
chr194464474344644803E08247314
chr194464488144646741E08247452