rs4810264

Homo sapiens
C>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0311 (9322/29922,GnomAD)
G=0295 (8602/29118,TOPMED)
G=0369 (1848/5008,1000G)
G=0355 (1370/3854,ALSPAC)
G=0350 (1298/3708,TWINSUK)
chr20:39391934 (GRCh38.p7) (20q12)
ND
GWASdb2
2   publication(s)
See rs on genome
2 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 20NC_000020.11:g.39391934C>G
GRCh37.p13 chr 20NC_000020.10:g.38020577C>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.856G=0.144
1000GenomesAmericanSub694C=0.440G=0.560
1000GenomesEast AsianSub1008C=0.611G=0.389
1000GenomesEuropeSub1006C=0.658G=0.342
1000GenomesGlobalStudy-wide5008C=0.631G=0.369
1000GenomesSouth AsianSub978C=0.460G=0.540
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.645G=0.355
The Genome Aggregation DatabaseAfricanSub8710C=0.819G=0.181
The Genome Aggregation DatabaseAmericanSub838C=0.360G=0.640
The Genome Aggregation DatabaseEast AsianSub1614C=0.591G=0.409
The Genome Aggregation DatabaseEuropeSub18458C=0.652G=0.347
The Genome Aggregation DatabaseGlobalStudy-wide29922C=0.688G=0.311
The Genome Aggregation DatabaseOtherSub302C=0.520G=0.480
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.704G=0.295
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.650G=0.350
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet
14740319Matching strategies for genetic association studies in structured populations.Hinds DAAm J Hum Genet

P-Value

SNP ID p-value Traits Study
rs48102640.000611nicotine dependence17158188

eQTL of rs4810264 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4810264 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr203803646238036625E07015885
chr203803700538037090E07016428