rs4816051

Homo sapiens
T>C / T>G
ANGPT4 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
G=0367 (10982/29912,GnomAD)
G=0383 (11160/29118,TOPMED)
G=0446 (2232/5008,1000G)
G=0297 (1146/3854,ALSPAC)
G=0296 (1097/3708,TWINSUK)
chr20:893106 (GRCh38.p7) (20p13)
ND
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 20NC_000020.11:g.893106T>C
GRCh38.p7 chr 20NC_000020.11:g.893106T>G
GRCh37.p13 chr 20NC_000020.10:g.873749T>C
GRCh37.p13 chr 20NC_000020.10:g.873749T>G

Gene: ANGPT4, angiopoietin 4(minus strand)

Molecule type Change Amino acid[Codon] SO Term
ANGPT4 transcript variant 2NM_001322809.1:c.N/AIntron Variant
ANGPT4 transcript variant 1NM_015985.3:c.N/AIntron Variant
ANGPT4 transcript variant X1XM_011529239.2:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.520G=0.480
1000GenomesAmericanSub694T=0.600G=0.400
1000GenomesEast AsianSub1008T=0.389G=0.611
1000GenomesEuropeSub1006T=0.725G=0.275
1000GenomesGlobalStudy-wide5008T=0.554G=0.446
1000GenomesSouth AsianSub978T=0.560G=0.440
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.703G=0.297
The Genome Aggregation DatabaseAfricanSub8708T=0.535G=0.465
The Genome Aggregation DatabaseAmericanSub838T=0.590G=0.41,
The Genome Aggregation DatabaseEast AsianSub1614T=0.390G=0.610
The Genome Aggregation DatabaseEuropeSub18450T=0.702G=0.297
The Genome Aggregation DatabaseGlobalStudy-wide29912T=0.632G=0.367
The Genome Aggregation DatabaseOtherSub302T=0.630G=0.37,
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.616G=0.383
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.704G=0.296
PMID Title Author Journal
22377092ANAPC1 and SLCO3A1 are associated with nicotine dependence: meta-analysis of genome-wide association studies.Wang KSDrug Alcohol Depend

P-Value

SNP ID p-value Traits Study
rs48160519.24E-05nicotine dependence (smoking)22377092

eQTL of rs4816051 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4816051 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.