rs4822791

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0303 (9085/29906,GnomAD)
A=0273 (7969/29116,TOPMED)
A=0324 (1621/5008,1000G)
A=0300 (1158/3854,ALSPAC)
A=0307 (1137/3708,TWINSUK)
chr22:26790358 (GRCh38.p7) (22q12.1)
AD
GWASdb2
1   publication(s)
See rs on genome
103 Enhancers around
15 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 22NC_000022.11:g.26790358G>A
GRCh37.p13 chr 22NC_000022.10:g.27186321G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.862A=0.138
1000GenomesAmericanSub694G=0.590A=0.410
1000GenomesEast AsianSub1008G=0.535A=0.465
1000GenomesEuropeSub1006G=0.645A=0.355
1000GenomesGlobalStudy-wide5008G=0.676A=0.324
1000GenomesSouth AsianSub978G=0.660A=0.340
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.700A=0.300
The Genome Aggregation DatabaseAfricanSub8706G=0.831A=0.169
The Genome Aggregation DatabaseAmericanSub838G=0.540A=0.460
The Genome Aggregation DatabaseEast AsianSub1614G=0.533A=0.467
The Genome Aggregation DatabaseEuropeSub18448G=0.655A=0.344
The Genome Aggregation DatabaseGlobalStudy-wide29906G=0.696A=0.303
The Genome Aggregation DatabaseOtherSub300G=0.610A=0.390
Trans-Omics for Precision MedicineGlobalStudy-wide29116G=0.726A=0.273
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.693A=0.307
PMID Title Author Journal
21956439Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q.Zuo LNeuropsychopharmacology

P-Value

SNP ID p-value Traits Study
rs48227915E-06alcohol dependence21956439

eQTL of rs4822791 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4822791 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr222715956127160640E067-25681
chr222714520427145255E068-41066
chr222714530527145368E068-40953
chr222714662827146961E068-39360
chr222714700127147922E068-38399
chr222715956127160640E068-25681
chr222715956127160640E069-25681
chr222714662827146961E070-39360
chr222714700127147922E070-38399
chr222715502827155078E070-31243
chr222715526327155317E070-31004
chr222715541427155464E070-30857
chr222715914227159397E070-26924
chr222715956127160640E070-25681
chr222716076927160832E070-25489
chr222716467827164760E070-21561
chr222717718427177242E070-9079
chr222717741627177476E070-8845
chr222717750327177961E070-8360
chr222717808027178296E070-8025
chr222718110427181220E070-5101
chr222718143427181484E070-4837
chr222718155627181606E070-4715
chr222719244527192517E0706124
chr222720065827201211E07014337
chr222720231727202383E07015996
chr222720260427202664E07016283
chr222720280927203114E07016488
chr222720328127203335E07016960
chr222720353627203674E07017215
chr222720447027204520E07018149
chr222720462827204715E07018307
chr222720513327205317E07018812
chr222720539227205570E07019071
chr222720572127205805E07019400
chr222720618227206280E07019861
chr222720642727206514E07020106
chr222720658927206675E07020268
chr222720678527207587E07020464
chr222720763627207965E07021315
chr222721181427211865E07025493
chr222721236227212474E07026041
chr222721260127213213E07026280
chr222722309527223145E07036774
chr222722316827223311E07036847
chr222722341927223951E07037098
chr222722674827226890E07040427
chr222722691327227057E07040592
chr222714662827146961E071-39360
chr222715956127160640E071-25681
chr222720065827201211E07114337
chr222714520427145255E072-41066
chr222714530527145368E072-40953
chr222714662827146961E072-39360
chr222714700127147922E072-38399
chr222714700127147922E073-38399
chr222715956127160640E073-25681
chr222719652727196617E07310206
chr222714662827146961E074-39360
chr222714700127147922E074-38399
chr222715956127160640E074-25681
chr222715246327152550E081-33771
chr222715255727153293E081-33028
chr222715956127160640E081-25681
chr222716076927160832E081-25489
chr222716102827161090E081-25231
chr222716467827164760E081-21561
chr222716502227165156E081-21165
chr222716519527165256E081-21065
chr222716533627165403E081-20918
chr222716557327165623E081-20698
chr222717741627177476E081-8845
chr222717750327177961E081-8360
chr222717808027178296E081-8025
chr222719170427191807E0815383
chr222719182027192295E0815499
chr222719231327192400E0815992
chr222719244527192517E0816124
chr222720260427202664E08116283
chr222720513327205317E08118812
chr222720539227205570E08119071
chr222720642727206514E08120106
chr222720658927206675E08120268
chr222720678527207587E08120464
chr222720763627207965E08121315
chr222722316827223311E08136847
chr222722341927223951E08137098
chr222722415627224196E08137835
chr222722423827224534E08137917
chr222716467827164760E082-21561
chr222718541927185469E082-852
chr222718563927185689E082-632
chr222718574327185793E082-528
chr222719614027196198E0829819
chr222720260427202664E08216283
chr222720280927203114E08216488
chr222720658927206675E08220268
chr222721260127213213E08226280
chr222722309527223145E08236774
chr222722316827223311E08236847
chr222722341927223951E08237098
chr222722415627224196E08237835
chr222722423827224534E08237917










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr222716323327163426E067-22895
chr222716351827164389E067-21932
chr222716323327163426E068-22895
chr222716351827164389E068-21932
chr222716323327163426E069-22895
chr222716351827164389E069-21932
chr222716351827164389E070-21932
chr222716351827164389E071-21932
chr222716323327163426E072-22895
chr222716351827164389E072-21932
chr222716351827164389E073-21932
chr222716323327163426E074-22895
chr222716351827164389E074-21932
chr222716323327163426E082-22895
chr222716351827164389E082-21932